Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Gene Enrichment

The table below show, solely based on the number of genes affected in a specific categroy, which classes are enriched (up) or depleted (down). Thje p-value is calculated according to 'GOToolBox: functional analysis of gene datasets based on Gene Ontology - David Martin, Christine Brun, Elisabeth Remy, Pierre Mouren, Denis Thieffry and Bernard Jacq'. We used the mouse-goa annotation from 2005 to perform this analysis.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

p Ratio description Accession neuronal

Results: HTML CSV LaTeX

Showing element 1 to 19 of 19 in total

neuronal	1

p	Ratio	description	
0.000000227862	down	olfactory receptor activity	
0.00115531	up	neuropeptide hormone activity	
0.00362499	down	metabotropic glutamate receptor signaling pathway	
0.00564318	up	dopamine receptor activity	
0.00670433	up	voltage-gated ion channel activity	
0.00774091	up	electron carrier activity	
0.00878703	up	nervous system development	
0.00916333	up	visual perception	
0.0100316	up	potassium ion binding	
0.0111584	down	metabotropic glutamate, GABA-B-like receptor activity	
0.0159483	up	sensory perception of sound	
0.0197922	down	sensory perception	
0.0202076	up	detection of stimulus during sensory perception	
0.0262113	up	neurotransmitter:sodium symporter activity	
0.0280274	up	synapse	
0.02908	up	calcium channel regulator activity	
0.0395988	up	axon ensheathment	
0.0395988	up	cannabinoid receptor activity	
0.0395988	up	neuropeptide receptor activity	

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- Part of neuralk circuitery.

- http://analysis.yellowcouch.org/