MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Gene Enrichment

The table below show, solely based on the number of genes affected in a specific categroy, which classes are enriched (up) or depleted (down). Thje p-value is calculated according to 'GOToolBox: functional analysis of gene datasets based on Gene Ontology - David Martin, Christine Brun, Elisabeth Remy, Pierre Mouren, Denis Thieffry and Bernard Jacq'. We used the mouse-goa annotation from 2005 to perform this analysis.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

p	Ratio	description	Accession	neuronal

Results: HTML CSV LaTeX

Showing element 1 to 50 of 201 in total

Ratio  : up

p	description	neuronal
0	small conjugating protein ligase activity	no value
	response to stimulus
	response to freezing
	protein binding
	membrane
	ice binding
	homoiothermy
	dephosphorylation
	cytoplasmic vesicle
0.00000000000532447	cytoplasm
0.000000005351	cell junction
0.0000000131078	RNA splicing
0.0000000750539	Golgi apparatus
0.00000117775	regulation of progression through cell cycle
0.00000824263	structural constituent of cell wall
0.0000171601	protein kinase activity
0.0000189325	phosphoric monoester hydrolase activity
0.0000244289	cell-cell signaling
0.0000321095	membrane fraction
0.0000520983	integral to plasma membrane
0.0000791323	protein C-terminus binding
0.000237102	nucleocytoplasmic transport
0.000408197	mRNA transport
	flagellin-based flagellum
0.000762333	protein dimerization activity
0.000793622	GTPase activity
0.000857538	glycerol metabolic process
0.000975592	transcription
0.00115531	neuropeptide hormone activity	1
0.00141209	extracellular region	no value
0.00235127	ciliary or flagellar motility
	arylamine N-acetyltransferase activity
	anion exchanger activity
0.0025796	regulation of transcription from RNA polymerase II promoter
	positive regulation of transcription
0.00308834	identical protein binding
0.00356939	signal transduction
0.00383965	nucleoside transporter activity
	membrane coat
	interleukin-1 receptor activity
	histamine receptor activity
	aldehyde dehydrogenase [NAD(P)+] activity
0.00391116	soluble fraction
0.00425207	cell cycle
0.00504034	mitosis
0.00564318	positive regulation of I-kappaB kinase/NF-kappaB cascade
	ligand-dependent nuclear receptor activity
	dopamine receptor activity	1
	circulation	no value
0.00614065	RNA polymerase II transcription factor activity

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- Accession is the GO accession key.
- Part of neuralk circuitery.