MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Gene Enrichment

The table below show, solely based on the number of genes affected in a specific categroy, which classes are enriched (up) or depleted (down). Thje p-value is calculated according to 'GOToolBox: functional analysis of gene datasets based on Gene Ontology - David Martin, Christine Brun, Elisabeth Remy, Pierre Mouren, Denis Thieffry and Bernard Jacq'. We used the mouse-goa annotation from 2005 to perform this analysis.

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Ratio	description	p	Accession	neuronal

Results: HTML CSV LaTeX

Showing element 51 to 100 of 239 in total

Ratio  : up

description	p	neuronal
arylamine N-acetyltransferase activity	0.00235127	no value
ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity	0.0202076
axon ensheathment	0.0395988	1
beta-galactoside alpha-2,3-sialyltransferase activity	0.0202076	no value
beta-mannosidase activity
calcium channel activity	0.0473076
calcium channel regulator activity	0.02908	1
calmodulin binding	0.0109353	no value
camera-type eye development	0.0202076
cannabinoid receptor activity	0.0395988	1
carotenoid biosynthetic process	0.0202076	no value
CD40 receptor binding
cell adhesion	0.0369324
cell cycle	0.00425207
cell growth	0.0493456
cell junction	0.000000005351
cell motility	0.0192954
cell proliferation	0.011406
cell-cell signaling	0.0000244289
cellular protein metabolic process	0.0395988
centrosome duplication	0.0202076
ceramide biosynthetic process	0.0395988
chromatin binding	0.0483241
chromosome, pericentric region	0.00970846
ciliary or flagellar motility	0.00235127
circulation	0.00564318
clathrin binding	0.0202076
cytoplasm	0.00000000000532447
cytoplasmic chromatin	0.0202076
cytoplasmic vesicle	0
cytoskeletal anchoring	0.0202076
delayed rectifier potassium channel activity
deoxyribonuclease II activity	0.0395988
dephosphorylation	0
detection of stimulus during sensory perception	0.0202076	1
dicarboxylic acid transport	0.0156029	no value
dopamine receptor activity	0.00564318	1
electron carrier activity	0.00774091
embryonic arm morphogenesis	0.0395988	no value
endodeoxyribonuclease activity	0.0202076
endoplasmic reticulum	0.0109032
ER-Golgi intermediate compartment	0.00774091
extracellular matrix	0.0192954
extracellular matrix binding	0.0202076
extracellular region	0.00141209
female pronucleus	0.0395988
fibroblast growth factor receptor signaling pathway	0.0127396
flagellin-based flagellum	0.000408197
generation of precursor metabolites and energy	0.0395988
glycerol metabolic process	0.000857538

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- Accession is the GO accession key.
- Part of neuralk circuitery.