Scientific

MK5 Microarray Data


Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Gene Enrichment

The table below show, solely based on the number of genes affected in a specific categroy, which classes are enriched (up) or depleted (down). Thje p-value is calculated according to 'GOToolBox: functional analysis of gene datasets based on Gene Ontology - David Martin, Christine Brun, Elisabeth Remy, Pierre Mouren, Denis Thieffry and Bernard Jacq'. We used the mouse-goa annotation from 2005 to perform this analysis.


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p description Ratio Accession neuronal
Results: HTML CSV LaTeX Showing element 1 to 19 of 19 in total
neuronal  : 1
p
description
Ratio
0.000000227862 olfactory receptor activity down
0.00115531 neuropeptide hormone activity up
0.00362499 metabotropic glutamate receptor signaling pathway down
0.00564318 dopamine receptor activity up
0.00670433 voltage-gated ion channel activity
0.00774091 electron carrier activity
0.00878703 nervous system development
0.00916333 visual perception
0.0100316 potassium ion binding
0.0111584 metabotropic glutamate, GABA-B-like receptor activity down
0.0159483 sensory perception of sound up
0.0197922 sensory perception down
0.0202076 detection of stimulus during sensory perception up
0.0262113 neurotransmitter:sodium symporter activity
0.0280274 synapse
0.02908 calcium channel regulator activity
0.0395988 axon ensheathment
cannabinoid receptor activity
neuropeptide receptor activity

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- Accession is the GO accession key.
- Part of neuralk circuitery.

- http://analysis.yellowcouch.org/