MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Gene Enrichment

The table below show, solely based on the number of genes affected in a specific categroy, which classes are enriched (up) or depleted (down). Thje p-value is calculated according to 'GOToolBox: functional analysis of gene datasets based on Gene Ontology - David Martin, Christine Brun, Elisabeth Remy, Pierre Mouren, Denis Thieffry and Bernard Jacq'. We used the mouse-goa annotation from 2005 to perform this analysis.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

neuronal	Ratio	p	description	Accession

Results: HTML CSV LaTeX

Showing element 151 to 200 of 239 in total

neuronal  : no value
Ratio  : up

p	description
0.0202076	tyrosine phosphorylation of STAT protein
	vitamin D receptor binding
	zygotic determination of anterior/posterior axis, embryo
0.023627	hormone activity
0.024391	protein complex assembly
0.0254395	integral to Golgi membrane
	response to drug
	transcription cofactor activity
0.0262113	anion transport
0.0322278	nucleotide binding
0.0328763	ribonuclease activity
0.0335097	ubiquitin cycle
0.0338741	protein homodimerization activity
0.0340565	inner ear morphogenesis
0.0354267	lipid metabolic process
0.0368141	antiporter activity
	inorganic anion exchanger activity
	negative regulation of protein kinase activity
0.0369324	cell adhesion
0.037387	plasma membrane
0.0374953	transcription factor activity
0.0382916	transcription from RNA polymerase II promoter
0.0395988	7S RNA binding
	activation of MAPKK activity
	adult heart development
	apical junction complex
	cellular protein metabolic process
	ceramide biosynthetic process
	deoxyribonuclease II activity
	embryonic arm morphogenesis
	female pronucleus
	generation of precursor metabolites and energy
	glycosaminoglycan binding
	growth hormone secretion
	hemostasis
	integral to peroxisomal membrane
	intercellular junction maintenance
	iron-sulfur cluster binding
	mannosidase activity
	methylated-DNA-[protein]-cysteine S-methyltransferase activity
	mitochondrial small ribosomal subunit
	mitotic G2 checkpoint
	monoamine transport
	myoblast fusion
	nuclear organization and biogenesis
	orexin receptor activity
	oxidized purine base lesion DNA N-glycosylase activity
	peroxisome organization and biogenesis
	phosphatidylinositol N-acetylglucosaminyltransferase activity
	phosphoinositide-mediated signaling

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- Accession is the GO accession key.
- Part of neuralk circuitery.