MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Gene Enrichment

The table below show, solely based on the number of genes affected in a specific categroy, which classes are enriched (up) or depleted (down). Thje p-value is calculated according to 'GOToolBox: functional analysis of gene datasets based on Gene Ontology - David Martin, Christine Brun, Elisabeth Remy, Pierre Mouren, Denis Thieffry and Bernard Jacq'. We used the mouse-goa annotation from 2005 to perform this analysis.

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description	Ratio	Accession	p	neuronal

Results: HTML CSV LaTeX

Showing element 51 to 100 of 239 in total

description	Ratio	p	neuronal
dephosphorylation	up	0	no value
detection of stimulus during sensory perception		0.0202076	1
dicarboxylic acid transport		0.0156029	no value
DNA replication	down	0.0291865
dopamine receptor activity	up	0.00564318	1
electron carrier activity		0.00774091
electron transport	down	0.0189449	no value
embryonic arm morphogenesis	up	0.0395988
endodeoxyribonuclease activity		0.0202076
endoplasmic reticulum		0.0109032
ER-Golgi intermediate compartment		0.00774091
external side of plasma membrane	down	0.00038871
extracellular matrix	up	0.0192954
extracellular matrix binding		0.0202076
extracellular region		0.00141209
extracellular space	down	4.41122e-18
female pronucleus	up	0.0395988
fibroblast growth factor receptor signaling pathway		0.0127396
flagellin-based flagellum		0.000408197
G-protein coupled receptor protein signaling pathway	down	0.0000325409
gamete generation		0.0350815
generation of precursor metabolites and energy	up	0.0395988
glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity	down	0.0040154
glycerol metabolic process	up	0.000857538
glycerophosphodiester phosphodiesterase activity		0.0127396
glycolysis	down	0.00369746
glycosaminoglycan binding	up	0.0395988
glyoxylate cycle		0.0202076
Golgi apparatus		0.0000000750539
Golgi stack	down	0.01078
growth hormone secretion	up	0.0395988
GTPase activity		0.000793622
guanyl nucleotide binding		0.00774091
hemostasis		0.0395988
histamine receptor activity		0.00383965
homoiothermy		0
hormone activity		0.023627
humoral immune response		0.0101128
ice binding		0
identical protein binding		0.00308834
inner ear morphogenesis		0.0340565
inorganic anion exchanger activity		0.0368141
integral to Golgi membrane		0.0254395
integral to membrane	down	0.000000909018
integral to peroxisomal membrane	up	0.0395988
integral to plasma membrane		0.0000520983
integrase activity	down	0.028596
intercellular junction maintenance	up	0.0395988
interleukin-1 receptor activity		0.00383965
interleukin-1 receptor complex		0.0202076

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- Accession is the GO accession key.
- Part of neuralk circuitery.