MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Gene Enrichment

The table below show, solely based on the number of genes affected in a specific categroy, which classes are enriched (up) or depleted (down). Thje p-value is calculated according to 'GOToolBox: functional analysis of gene datasets based on Gene Ontology - David Martin, Christine Brun, Elisabeth Remy, Pierre Mouren, Denis Thieffry and Bernard Jacq'. We used the mouse-goa annotation from 2005 to perform this analysis.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

description	p	Ratio	Accession	neuronal

Results: HTML CSV LaTeX

Showing element 41 to 90 of 239 in total

description	p	Ratio	neuronal
chymotrypsin activity	0.0175073	down	no value
ciliary or flagellar motility	0.00235127	up
circulation	0.00564318
clathrin binding	0.0202076
cytoplasm	0.00000000000532447
cytoplasmic chromatin	0.0202076
cytoplasmic vesicle	0
cytoskeletal anchoring	0.0202076
delayed rectifier potassium channel activity
deoxyribonuclease II activity	0.0395988
dephosphorylation	0
detection of stimulus during sensory perception	0.0202076		1
dicarboxylic acid transport	0.0156029		no value
DNA replication	0.0291865	down
dopamine receptor activity	0.00564318	up	1
electron carrier activity	0.00774091
electron transport	0.0189449	down	no value
embryonic arm morphogenesis	0.0395988	up
endodeoxyribonuclease activity	0.0202076
endoplasmic reticulum	0.0109032
ER-Golgi intermediate compartment	0.00774091
external side of plasma membrane	0.00038871	down
extracellular matrix	0.0192954	up
extracellular matrix binding	0.0202076
extracellular region	0.00141209
extracellular space	4.41122e-18	down
female pronucleus	0.0395988	up
fibroblast growth factor receptor signaling pathway	0.0127396
flagellin-based flagellum	0.000408197
G-protein coupled receptor protein signaling pathway	0.0000325409	down
gamete generation	0.0350815
generation of precursor metabolites and energy	0.0395988	up
glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity	0.0040154	down
glycerol metabolic process	0.000857538	up
glycerophosphodiester phosphodiesterase activity	0.0127396
glycolysis	0.00369746	down
glycosaminoglycan binding	0.0395988	up
glyoxylate cycle	0.0202076
Golgi apparatus	0.0000000750539
Golgi stack	0.01078	down
growth hormone secretion	0.0395988	up
GTPase activity	0.000793622
guanyl nucleotide binding	0.00774091
hemostasis	0.0395988
histamine receptor activity	0.00383965
homoiothermy	0
hormone activity	0.023627
humoral immune response	0.0101128
ice binding	0
identical protein binding	0.00308834

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- Accession is the GO accession key.
- Part of neuralk circuitery.