MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Gene Enrichment

The table below show, solely based on the number of genes affected in a specific categroy, which classes are enriched (up) or depleted (down). Thje p-value is calculated according to 'GOToolBox: functional analysis of gene datasets based on Gene Ontology - David Martin, Christine Brun, Elisabeth Remy, Pierre Mouren, Denis Thieffry and Bernard Jacq'. We used the mouse-goa annotation from 2005 to perform this analysis.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

p	neuronal	Accession	description	Ratio

Results: HTML CSV LaTeX

Showing element 41 to 90 of 239 in total

p	neuronal	description	Ratio
0.000793622	no value	GTPase activity	up
0.000857538		glycerol metabolic process
0.000975592		transcription
0.00115531	1	neuropeptide hormone activity
0.00123417	no value	ATP binding	down
0.00127674		antigen binding
0.00141209		extracellular region	up
0.00235127		anion exchanger activity
		arylamine N-acetyltransferase activity
		ciliary or flagellar motility
0.00245746		NAD binding	down
0.0025796		positive regulation of transcription	up
		regulation of transcription from RNA polymerase II promoter
0.00273397		ubiquitin-protein ligase activity	down
0.00308834		identical protein binding	up
0.00356939		signal transduction
0.00362499	1	metabotropic glutamate receptor signaling pathway	down
0.00369746	no value	glycolysis
0.00383965		aldehyde dehydrogenase [NAD(P)+] activity	up
		histamine receptor activity
		interleukin-1 receptor activity
		membrane coat
		nucleoside transporter activity
0.00391116		soluble fraction
0.0040154		glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity	down
0.00425207		cell cycle	up
0.00504034		mitosis
0.00564318		circulation
		ligand-dependent nuclear receptor activity
		positive regulation of I-kappaB kinase/NF-kappaB cascade
	1	dopamine receptor activity
0.00614065	no value	RNA polymerase II transcription factor activity
0.00664368		negative regulation of cell growth
0.00670433	1	voltage-gated ion channel activity
0.00718696	no value	regulation of transcription, DNA-dependent	down
0.00726676		multicellular organismal development	up
0.00759448		protein serine/threonine phosphatase activity
0.00774091		acetyltransferase activity
		ER-Golgi intermediate compartment
		guanyl nucleotide binding
		positive regulation of body size
		retinoic acid metabolic process
	1	electron carrier activity
0.00803044	no value	binding	down
0.00833399		regulation of transcription	up
0.00836988		intracellular
0.00878703	1	nervous system development
0.00916333		visual perception
0.00965867	no value	mitochondrion	down
0.00970846		chromosome, pericentric region	up

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- Accession is the GO accession key.
- Part of neuralk circuitery.