MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Gene Enrichment

The table below show, solely based on the number of genes affected in a specific categroy, which classes are enriched (up) or depleted (down). Thje p-value is calculated according to 'GOToolBox: functional analysis of gene datasets based on Gene Ontology - David Martin, Christine Brun, Elisabeth Remy, Pierre Mouren, Denis Thieffry and Bernard Jacq'. We used the mouse-goa annotation from 2005 to perform this analysis.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Ratio	p	description	Accession	neuronal

Results: HTML CSV LaTeX

Showing element 22 to 71 of 239 in total

Ratio	p	description	neuronal
down	0.0040154	glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity	no value
	0.00718696	regulation of transcription, DNA-dependent
	0.00803044	binding
	0.00965867	mitochondrion
	0.0105006	trypsin activity
	0.01078	Golgi stack
	0.0111584	metabotropic glutamate, GABA-B-like receptor activity	1
	0.0175073	chymotrypsin activity	no value
	0.0189449	electron transport
	0.0197922	sensory perception	1
	0.0204393	proteolysis	no value
	0.0206183	microtubule-based movement
	0.0216681	kinase activity
	0.028596	integrase activity
	0.0291865	DNA replication
	0.0350815	gamete generation
	0.0377184	transferase activity
up	0	cytoplasmic vesicle
		dephosphorylation
		homoiothermy
		ice binding
		membrane
		protein binding
		response to freezing
		response to stimulus
		small conjugating protein ligase activity
	0.00000000000532447	cytoplasm
	0.000000005351	cell junction
	0.0000000131078	RNA splicing
	0.0000000750539	Golgi apparatus
	0.00000117775	regulation of progression through cell cycle
	0.00000824263	structural constituent of cell wall
	0.0000171601	protein kinase activity
	0.0000189325	phosphoric monoester hydrolase activity
	0.0000244289	cell-cell signaling
	0.0000321095	membrane fraction
	0.0000520983	integral to plasma membrane
	0.0000791323	protein C-terminus binding
	0.000237102	nucleocytoplasmic transport
	0.000408197	flagellin-based flagellum
		mRNA transport
	0.000762333	protein dimerization activity
	0.000793622	GTPase activity
	0.000857538	glycerol metabolic process
	0.000975592	transcription
	0.00115531	neuropeptide hormone activity	1
	0.00141209	extracellular region	no value
	0.00235127	anion exchanger activity
		arylamine N-acetyltransferase activity
		ciliary or flagellar motility

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- Accession is the GO accession key.
- Part of neuralk circuitery.