MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Gene Enrichment

The table below show, solely based on the number of genes affected in a specific categroy, which classes are enriched (up) or depleted (down). Thje p-value is calculated according to 'GOToolBox: functional analysis of gene datasets based on Gene Ontology - David Martin, Christine Brun, Elisabeth Remy, Pierre Mouren, Denis Thieffry and Bernard Jacq'. We used the mouse-goa annotation from 2005 to perform this analysis.

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

p	Accession	neuronal	Ratio	description

Results: HTML CSV LaTeX

Showing element 41 to 90 of 239 in total

p	neuronal	Ratio	description
0.000793622	no value	up	GTPase activity
0.000857538			glycerol metabolic process
0.000975592			transcription
0.00115531	1		neuropeptide hormone activity
0.00123417	no value	down	ATP binding
0.00127674			antigen binding
0.00141209		up	extracellular region
0.00235127			anion exchanger activity
			arylamine N-acetyltransferase activity
			ciliary or flagellar motility
0.00245746		down	NAD binding
0.0025796		up	positive regulation of transcription
			regulation of transcription from RNA polymerase II promoter
0.00273397		down	ubiquitin-protein ligase activity
0.00308834		up	identical protein binding
0.00356939			signal transduction
0.00362499	1	down	metabotropic glutamate receptor signaling pathway
0.00369746	no value		glycolysis
0.00383965		up	aldehyde dehydrogenase [NAD(P)+] activity
			histamine receptor activity
			interleukin-1 receptor activity
			membrane coat
			nucleoside transporter activity
0.00391116			soluble fraction
0.0040154		down	glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity
0.00425207		up	cell cycle
0.00504034			mitosis
0.00564318			circulation
			ligand-dependent nuclear receptor activity
			positive regulation of I-kappaB kinase/NF-kappaB cascade
	1		dopamine receptor activity
0.00614065	no value		RNA polymerase II transcription factor activity
0.00664368			negative regulation of cell growth
0.00670433	1		voltage-gated ion channel activity
0.00718696	no value	down	regulation of transcription, DNA-dependent
0.00726676		up	multicellular organismal development
0.00759448			protein serine/threonine phosphatase activity
0.00774091			acetyltransferase activity
			ER-Golgi intermediate compartment
			guanyl nucleotide binding
			positive regulation of body size
			retinoic acid metabolic process
	1		electron carrier activity
0.00803044	no value	down	binding
0.00833399		up	regulation of transcription
0.00836988			intracellular
0.00878703	1		nervous system development
0.00916333			visual perception
0.00965867	no value	down	mitochondrion
0.00970846		up	chromosome, pericentric region

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- Accession is the GO accession key.
- Part of neuralk circuitery.