MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Gene Enrichment

The table below show, solely based on the number of genes affected in a specific categroy, which classes are enriched (up) or depleted (down). Thje p-value is calculated according to 'GOToolBox: functional analysis of gene datasets based on Gene Ontology - David Martin, Christine Brun, Elisabeth Remy, Pierre Mouren, Denis Thieffry and Bernard Jacq'. We used the mouse-goa annotation from 2005 to perform this analysis.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

p	Ratio	description	neuronal	Accession

Results: HTML CSV LaTeX

Showing element 122 to 171 of 239 in total

p	Ratio	description	neuronal
0.0202076	up	beta-galactoside alpha-2,3-sialyltransferase activity	no value
		beta-mannosidase activity
		camera-type eye development
		carotenoid biosynthetic process
		CD40 receptor binding
		centrosome duplication
		clathrin binding
		cytoplasmic chromatin
		cytoskeletal anchoring
		delayed rectifier potassium channel activity
		detection of stimulus during sensory perception	1
		endodeoxyribonuclease activity	no value
		extracellular matrix binding
		glyoxylate cycle
		interleukin-1 receptor complex
		interleukin-18 receptor complex
		leading edge cell differentiation
		leukocyte activation
		leukocyte adhesion
		male pronucleus
		methyl-CpG binding
		monoamine transporter activity
		oocyte differentiation
		osmosensory signaling pathway
		phosphatidylinositol-3,4,5-triphosphate binding
		positive regulation of receptor mediated endocytosis
		positive regulation of smooth muscle contraction
		positive regulation of vasoconstriction
		protein kinase C inhibitor activity
		protein phosphatase type 2A activity
		regulation of viral transcription
		RNA lariat debranching enzyme activity
		selenocysteine incorporation
		transcription from RNA polymerase III promoter
		transport vesicle
		tyrosine phosphorylation of STAT protein
		vitamin D receptor binding
		zygotic determination of anterior/posterior axis, embryo
0.0204393	down	proteolysis
0.0206183		microtubule-based movement
0.0216681		kinase activity
0.023627	up	hormone activity
0.024391		protein complex assembly
0.0254395		integral to Golgi membrane
		response to drug
		transcription cofactor activity
0.0262113		anion transport
		neurotransmitter:sodium symporter activity	1
0.0280274		synapse
0.028596	down	integrase activity	no value

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- Accession is the GO accession key.
- Part of neuralk circuitery.