MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Gene Enrichment

The table below show, solely based on the number of genes affected in a specific categroy, which classes are enriched (up) or depleted (down). Thje p-value is calculated according to 'GOToolBox: functional analysis of gene datasets based on Gene Ontology - David Martin, Christine Brun, Elisabeth Remy, Pierre Mouren, Denis Thieffry and Bernard Jacq'. We used the mouse-goa annotation from 2005 to perform this analysis.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

description	Ratio	p	Accession	neuronal

Results: HTML CSV LaTeX

Showing element 1 to 19 of 19 in total

neuronal  : 1

description	Ratio	p
axon ensheathment	up	0.0395988
calcium channel regulator activity		0.02908
cannabinoid receptor activity		0.0395988
detection of stimulus during sensory perception		0.0202076
dopamine receptor activity		0.00564318
electron carrier activity		0.00774091
metabotropic glutamate receptor signaling pathway	down	0.00362499
metabotropic glutamate, GABA-B-like receptor activity		0.0111584
nervous system development	up	0.00878703
neuropeptide hormone activity		0.00115531
neuropeptide receptor activity		0.0395988
neurotransmitter:sodium symporter activity		0.0262113
olfactory receptor activity	down	0.000000227862
potassium ion binding	up	0.0100316
sensory perception	down	0.0197922
sensory perception of sound	up	0.0159483
synapse		0.0280274
visual perception		0.00916333
voltage-gated ion channel activity		0.00670433

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- Accession is the GO accession key.
- Part of neuralk circuitery.