MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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Ratio	Regulation	description	Gene Ontology	Class	Gene	Accession	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 51 to 100 of 2667 in total

Ratio	Regulation	description	Gene Ontology	Class
1.11519	up	eukaryotic translation initiation factor 4E family member 1B (EIF4E1B), mRNA [RefSeq_dna;Acc:NM_001099408]	translation initiation factor activity	molecular function
			translational initiation	biological process
1.11956	down	Protein RER1. [Uniprot/SWISSPROT;Acc:O15258]	Golgi apparatus	cellular component
			integral to Golgi membrane
			integral to membrane
			membrane
			molecular_function	molecular function
			retrograde vesicle-mediated transport, Golgi to ER	biological process
1.12417	up	Protein CutA precursor (Brain acetylcholinesterase putative membrane anchor) (Acetylcholinesterase-associated protein). [Uniprot/SWISSPROT;Acc:O60888]	enzyme binding	molecular function
			membrane	cellular component
			protein heterodimerization activity	molecular function
			protein homooligomerization	biological process
			protein localization
			response to metal ion
			retinoic acid receptor binding	molecular function
			retinoid-X receptor activity
			thyroid hormone receptor binding
			thyroid hormone receptor coactivator activity
			vitamin D receptor binding
1.1243	down	Zinc finger protein basonuclin-2. [Uniprot/SWISSPROT;Acc:Q6ZN30]	DNA binding
			intracellular	cellular component
			metal ion binding	molecular function
			nucleic acid binding
			nucleus	cellular component
			regulation of transcription, DNA-dependent	biological process
			transcription
			zinc ion binding	molecular function
1.13007	up	Zinc finger protein 219. [Uniprot/SWISSPROT;Acc:Q9P2Y4]	anion transport	biological process
			G-protein coupled receptor protein signaling pathway
			histamine receptor activity	molecular function
			inorganic anion exchanger activity
			integral to membrane	cellular component
			intracellular
			membrane
			metal ion binding	molecular function
			nucleic acid binding
			nucleus	cellular component
			regulation of transcription, DNA-dependent	biological process
			transcription factor activity	molecular function
			zinc ion binding
1.13541	down	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2). [Uniprot/SWISSPROT;Acc:Q99435]	blood coagulation	biological process
			calcium ion binding	molecular function
			cell adhesion	biological process
			extracellular region	cellular component
			membrane
			protein binding	molecular function
			regulation of growth	biological process
			structural molecule activity	molecular function
			transmembrane receptor activity
1.14311		14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1). [Uniprot/SWISSPROT;Acc:P61981]	cytoplasm	cellular component

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.