Scientific
MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis
These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.
Affected Genes

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Ratio Regulation description Class Gene Ontology Gene Accession Minimum Ratio Maximum Ratio
Results: HTML CSV LaTeX
Showing element 101 to 150 of 2667 in total

\def\wcA{0.16666666666667\textwidth}
\def\wcB{0.16666666666667\textwidth}
\def\wcC{0.16666666666667\textwidth}
\def\wcD{0.16666666666667\textwidth}
\def\wcE{0.16666666666667\textwidth}
\begin{longtable}{|c|c|c|c|c|}
\hline
\parbox{\wcA}{\vspace{3pt}\noindent
Ratio\vspace{3pt}}&\parbox{\wcB}{\vspace{3pt}\noindent
Regulation\vspace{3pt}}&\parbox{\wcC}{\vspace{3pt}\noindent
description\vspace{3pt}}&\parbox{\wcD}{\vspace{3pt}\noindent
Class\vspace{3pt}}&\parbox{\wcE}{\vspace{3pt}\noindent
Gene Ontology\vspace{3pt}}\\
\hline
\hline
\multirow{9}{*}{\parbox{\wcA}{\vspace{3pt}\noindent
1.14311\vspace{3pt}}}&\multirow{9}{*}{\parbox{\wcB}{\vspace{3pt}\noindent
down\vspace{3pt}}}&\multirow{9}{*}{\parbox{\wcC}{\vspace{3pt}\noindent
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1). \vspace{3pt}}}&\multirow{4}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
biological process\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
protein targeting\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
regulation of neuron differentiation\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
regulation of signal transduction\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
regulation of synaptic plasticity\vspace{3pt}}\\\cline{4-5}
&&&\parbox{\wcD}{\vspace{3pt}\noindent
cellular component\vspace{3pt}}&\parbox{\wcE}{\vspace{3pt}\noindent
cytoplasm\vspace{3pt}}\\\cline{4-5}
&&&\multirow{4}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
molecular function\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
insulin-like growth factor receptor binding\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
protein domain specific binding\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
protein kinase C binding\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
protein kinase C inhibitor activity\vspace{3pt}}\\\hline
\multirow{6}{*}{\parbox{\wcA}{\vspace{3pt}\noindent
1.14915\vspace{3pt}}}&\multirow{13}{*}{\parbox{\wcB}{\vspace{3pt}\noindent
up\vspace{3pt}}}&\multirow{6}{*}{\parbox{\wcC}{\vspace{3pt}\noindent
Transmembrane emp24 domain-containing protein 1 precursor (Interleukin-1 receptor-like 1 ligand) (Putative T1/ST2 receptor- binding protein). \vspace{3pt}}}&\multirow{3}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
biological process\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
cell-cell signaling\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
signal transduction\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
transport\vspace{3pt}}\\\cline{4-5}
&&&\multirow{2}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
cellular component\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
integral to membrane\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
membrane\vspace{3pt}}\\\cline{4-5}
&&&\parbox{\wcD}{\vspace{3pt}\noindent
molecular function\vspace{3pt}}&\parbox{\wcE}{\vspace{3pt}\noindent
receptor binding\vspace{3pt}}\\\cline{1-1}\cline{3-5}
\multirow{7}{*}{\parbox{\wcA}{\vspace{3pt}\noindent
1.15279\vspace{3pt}}}&&\multirow{7}{*}{\parbox{\wcC}{\vspace{3pt}\noindent
Podocalyxin-like protein 2 precursor (Endoglycan). \vspace{3pt}}}&\parbox{\wcD}{\vspace{3pt}\noindent
biological process\vspace{3pt}}&\parbox{\wcE}{\vspace{3pt}\noindent
cell adhesion\vspace{3pt}}\\\cline{4-5}
&&&\multirow{3}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
cellular component\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
integral to plasma membrane\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
membrane\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
viral capsid\vspace{3pt}}\\\cline{4-5}
&&&\multirow{3}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
molecular function\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
glycosaminoglycan binding\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
protein binding\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
structural molecule activity\vspace{3pt}}\\\hline
\multirow{7}{*}{\parbox{\wcA}{\vspace{3pt}\noindent
1.1611\vspace{3pt}}}&\multirow{7}{*}{\parbox{\wcB}{\vspace{3pt}\noindent
down\vspace{3pt}}}&\multirow{7}{*}{\parbox{\wcC}{\vspace{3pt}\noindent
Guanylin precursor (Guanylate cyclase activator 2A) (Guanylate cyclase-activating protein 1) (Gap-I) [Contains: HMW-guanylin; Guanylin]. \vspace{3pt}}}&\multirow{2}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
biological process\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
electron transport\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
signal transduction\vspace{3pt}}\\\cline{4-5}
&&&\parbox{\wcD}{\vspace{3pt}\noindent
cellular component\vspace{3pt}}&\parbox{\wcE}{\vspace{3pt}\noindent
extracellular region\vspace{3pt}}\\\cline{4-5}
&&&\multirow{4}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
molecular function\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
electron carrier activity\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
enzyme activator activity\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
guanylate cyclase activator activity\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
hormone activity\vspace{3pt}}\\\hline
\multirow{5}{*}{\parbox{\wcA}{\vspace{3pt}\noindent
1.16158\vspace{3pt}}}&\multirow{21}{*}{\parbox{\wcB}{\vspace{3pt}\noindent
up\vspace{3pt}}}&\multirow{5}{*}{\parbox{\wcC}{\vspace{3pt}\noindent
transient receptor potential cation channel, subfamily C, member 2 (TRPC2) on chromosome 11 \vspace{3pt}}}&\multirow{2}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
biological process\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
calcium ion transport\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
ion transport\vspace{3pt}}\\\cline{4-5}
&&&\parbox{\wcD}{\vspace{3pt}\noindent
cellular component\vspace{3pt}}&\parbox{\wcE}{\vspace{3pt}\noindent
membrane\vspace{3pt}}\\\cline{4-5}
&&&\multirow{3}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
molecular function\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
calcium channel activity\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
ion channel activity\vspace{3pt}}\\\cline{1-1}\cline{3-3}\cline{5-5}
\parbox{\wcA}{\vspace{3pt}\noindent
1.16173\vspace{3pt}}&&\parbox{\wcC}{\vspace{3pt}\noindent
oligonucleotide/oligosaccharide-binding fold containing 2B \vspace{3pt}}&&\parbox{\wcE}{\vspace{3pt}\noindent
nucleic acid binding\vspace{3pt}}\\\cline{1-1}\cline{3-5}
\multirow{2}{*}{\parbox{\wcA}{\vspace{3pt}\noindent
1.16363\vspace{3pt}}}&&\multirow{2}{*}{\parbox{\wcC}{\vspace{3pt}\noindent
Sperm acrosome membrane-associated protein 1 precursor (Sperm acrosomal membrane-associated protein 32). \vspace{3pt}}}&\multirow{2}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
cellular component\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
integral to membrane\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
membrane\vspace{3pt}}\\\cline{1-1}\cline{3-5}
\multirow{4}{*}{\parbox{\wcA}{\vspace{3pt}\noindent
1.16393\vspace{3pt}}}&&\multirow{4}{*}{\parbox{\wcC}{\vspace{3pt}\noindent
olfactory receptor, family 5, subfamily K, member 4 \vspace{3pt}}}&\parbox{\wcD}{\vspace{3pt}\noindent
biological process\vspace{3pt}}&\parbox{\wcE}{\vspace{3pt}\noindent
G-protein coupled receptor protein signaling pathway\vspace{3pt}}\\\cline{4-5}
&&&\parbox{\wcD}{\vspace{3pt}\noindent
cellular component\vspace{3pt}}&\parbox{\wcE}{\vspace{3pt}\noindent
integral to membrane\vspace{3pt}}\\\cline{4-5}
&&&\multirow{2}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
molecular function\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
olfactory receptor activity\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
rhodopsin-like receptor activity\vspace{3pt}}\\\cline{1-1}\cline{3-5}
\multirow{9}{*}{\parbox{\wcA}{\vspace{3pt}\noindent
1.16499\vspace{3pt}}}&&\multirow{9}{*}{\parbox{\wcC}{\vspace{3pt}\noindent
ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3). \vspace{3pt}}}&\multirow{4}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
biological process\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
cell adhesion\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
central nervous system development\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
negative regulation of cell adhesion\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
proteolysis\vspace{3pt}}\\\cline{4-5}
&&&\multirow{2}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
cellular component\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
integral to membrane\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
membrane\vspace{3pt}}\\\cline{4-5}
&&&\multirow{3}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
molecular function\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
integrin binding\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
metalloendopeptidase activity\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
protein binding\vspace{3pt}}\\\hline
nd{longtable}

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.

 - The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells. 

 - The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component. 

 - The Gene Ontology terms as linked to the specific gene.

 - Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray

 - Accession is the GO accession key. 

 - Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.

 - Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- http://analysis.yellowcouch.org/