Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Ratio Regulation description Class Gene Ontology Gene Accession Minimum Ratio Maximum Ratio

Results: HTML CSV LaTeX

Showing element 501 to 550 of 2667 in total


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\begin{longtable}{|c|c|c|c|c|}
\hline
\parbox{\wcA}{\vspace{3pt}\noindent
Ratio\vspace{3pt}}&\parbox{\wcB}{\vspace{3pt}\noindent
Regulation\vspace{3pt}}&\parbox{\wcC}{\vspace{3pt}\noindent
description\vspace{3pt}}&\parbox{\wcD}{\vspace{3pt}\noindent
Class\vspace{3pt}}&\parbox{\wcE}{\vspace{3pt}\noindent
Gene Ontology\vspace{3pt}}\\
\hline
\hline
\multirow{7}{*}{\parbox{\wcA}{\vspace{3pt}\noindent
1.24114\vspace{3pt}}}&\multirow{42}{*}{\parbox{\wcB}{\vspace{3pt}\noindent
down\vspace{3pt}}}&\multirow{7}{*}{\parbox{\wcC}{\vspace{3pt}\noindent
Myosin-15 (Myosin heavy chain 15). \vspace{3pt}}}&\multirow{2}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
cellular component\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
myosin complex\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
striated muscle thick filament\vspace{3pt}}\\\cline{4-5}
&&&\multirow{5}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
molecular function\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
actin binding\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
ATP binding\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
calmodulin binding\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
motor activity\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
nucleotide binding\vspace{3pt}}\\\cline{1-1}\cline{3-5}
\multirow{8}{*}{\parbox{\wcA}{\vspace{3pt}\noindent
1.24359\vspace{3pt}}}&&\multirow{8}{*}{\parbox{\wcC}{\vspace{3pt}\noindent
Calcium-dependent secretion activator 2 (Calcium-dependent activator protein for secretion 2) (CAPS-2). \vspace{3pt}}}&\multirow{2}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
biological process\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
exocytosis\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
protein transport\vspace{3pt}}\\\cline{4-5}
&&&\multirow{4}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
cellular component\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
cell junction\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
cytoplasmic vesicle\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
membrane\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
synapse\vspace{3pt}}\\\cline{4-5}
&&&\multirow{2}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
molecular function\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
calcium ion binding\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
lipid binding\vspace{3pt}}\\\cline{1-1}\cline{3-5}
\multirow{12}{*}{\parbox{\wcA}{\vspace{3pt}\noindent
1.24361\vspace{3pt}}}&&\multirow{12}{*}{\parbox{\wcC}{\vspace{3pt}\noindent
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA (EC 3.2.1.113) (Processing alpha-1,2-mannosidase IA) (Alpha-1,2-mannosidase IA) (Mannosidase alpha class 1A member 1) (Man(9)-alpha-mannosidase) (Man9-mannosidase). \vspace{3pt}}}&\multirow{2}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
biological process\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
metabolic process\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
protein amino acid glycosylation\vspace{3pt}}\\\cline{4-5}
&&&\multirow{6}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
cellular component\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
endoplasmic reticulum\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
ER-Golgi intermediate compartment\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
Golgi apparatus\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
integral to membrane\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
membrane\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
membrane fraction\vspace{3pt}}\\\cline{4-5}
&&&\multirow{4}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
molecular function\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
calcium ion binding\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
hydrolase activity, acting on glycosyl bonds\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
mannosidase activity\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
mannosyl-oligosaccharide 1,2-alpha-mannosidase activity\vspace{3pt}}\\\cline{1-1}\cline{3-5}
\multirow{7}{*}{\parbox{\wcA}{\vspace{3pt}\noindent
1.24964\vspace{3pt}}}&&\multirow{7}{*}{\parbox{\wcC}{\vspace{3pt}\noindent
Atlastin-2 (ADP-ribosylation factor-like protein 6-interacting protein 2). \vspace{3pt}}}&\parbox{\wcD}{\vspace{3pt}\noindent
biological process\vspace{3pt}}&\parbox{\wcE}{\vspace{3pt}\noindent
immune response\vspace{3pt}}\\\cline{4-5}
&&&\multirow{2}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
cellular component\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
integral to membrane\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
membrane\vspace{3pt}}\\\cline{4-5}
&&&\multirow{4}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
molecular function\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
GTP binding\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
GTPase activity\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
nucleotide binding\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
protein binding\vspace{3pt}}\\\cline{1-1}\cline{3-5}
\multirow{8}{*}{\parbox{\wcA}{\vspace{3pt}\noindent
1.25113\vspace{3pt}}}&&\multirow{8}{*}{\parbox{\wcC}{\vspace{3pt}\noindent
Zinc finger protein OZF (Only zinc finger protein) (Zinc finger protein 146). \vspace{3pt}}}&\parbox{\wcD}{\vspace{3pt}\noindent
biological process\vspace{3pt}}&\parbox{\wcE}{\vspace{3pt}\noindent
regulation of transcription, DNA-dependent\vspace{3pt}}\\\cline{4-5}
&&&\multirow{2}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
cellular component\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
intracellular\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
nucleus\vspace{3pt}}\\\cline{4-5}
&&&\multirow{5}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
molecular function\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
DNA binding\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
heparin binding\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
metal ion binding\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
nucleic acid binding\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
zinc ion binding\vspace{3pt}}\\\hline
\multirow{8}{*}{\parbox{\wcA}{\vspace{3pt}\noindent
1.25147\vspace{3pt}}}&\multirow{8}{*}{\parbox{\wcB}{\vspace{3pt}\noindent
up\vspace{3pt}}}&\multirow{8}{*}{\parbox{\wcC}{\vspace{3pt}\noindent
T-lymphocyte activation antigen CD86 precursor (Activation B7-2 antigen) (CTLA-4 counter-receptor B7.2) (B70) (FUN-1) (BU63). \vspace{3pt}}}&\multirow{8}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
biological process\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
cell-cell signaling\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
immune response\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
positive regulation of cell proliferation\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
positive regulation of interleukin-2 biosynthetic process\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
positive regulation of interleukin-4 biosynthetic process\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
positive regulation of lymphotoxin A biosynthetic process\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
positive regulation of T-helper 2 cell differentiation\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
positive regulation of transcription\vspace{3pt}}\\\hline
nd{longtable}

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.

 - The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells. 

 - The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component. 

 - The Gene Ontology terms as linked to the specific gene.

 - Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray

 - Accession is the GO accession key. 

 - Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.

 - Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.

- http://analysis.yellowcouch.org/