MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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description	Ratio	Regulation	Class	Gene Ontology	Gene	Accession	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 2619 to 2667 of 2667 in total

description	Ratio	Regulation	Class	Gene Ontology
Zinc finger protein 384 (Nuclear matrix transcription factor 4) (Nuclear matrix protein 4) (CAG repeat protein 1) (CAS-interacting zinc finger protein) (Trinucleotide repeat-containing gene 1 protein). [Uniprot/SWISSPROT;Acc:Q8TF68]	1.59188	up	biological process	regulation of transcription, DNA-dependent
				transcription
			cellular component	intracellular
				nucleus
			molecular function	DNA binding
				metal ion binding
				nucleic acid binding
				zinc ion binding
Zinc finger protein basonuclin-2. [Uniprot/SWISSPROT;Acc:Q6ZN30]	1.1243	down	biological process	regulation of transcription, DNA-dependent
				transcription
			cellular component	intracellular
				nucleus
			molecular function	DNA binding
				metal ion binding
				nucleic acid binding
				zinc ion binding
Zinc finger protein OZF (Only zinc finger protein) (Zinc finger protein 146). [Uniprot/SWISSPROT;Acc:Q15072]	1.25113		biological process	regulation of transcription, DNA-dependent
			cellular component	intracellular
				nucleus
			molecular function	DNA binding
				heparin binding
				metal ion binding
				nucleic acid binding
				zinc ion binding
Zinc finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2). [Uniprot/SWISSPROT;Acc:Q92785]	1.93995	up	biological process	apoptosis
				induction of apoptosis by extracellular signals
				regulation of transcription, DNA-dependent
				transcription
			cellular component	cytoplasm
				intracellular
				nucleus
			molecular function	metal ion binding
				nucleic acid binding
				protein binding
				zinc ion binding
Zinc finger SWIM domain-containing protein 3. [Uniprot/SWISSPROT;Acc:Q96MP5]	1.56335			metal ion binding
				zinc ion binding
zinc finger, FYVE domain containing 26 [RefSeq_peptide;Acc:NP_056161]	4.87049		cellular component	intracellular
			molecular function	metal ion binding
				nucleic acid binding
				zinc ion binding
zinc transporter like 2 [RefSeq_peptide;Acc:NP_598003]	2.45764		biological process	cation transport
				zinc ion transport
			cellular component	cytoplasmic membrane-bound vesicle
				Golgi apparatus
				membrane
			molecular function	cation transporter activity
				protein binding
				zinc ion transporter activity

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.