Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes


Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Ratio Regulation description Class Gene Ontology Gene Accession Minimum Ratio Maximum Ratio
Results: HTML CSV LaTeX Showing element 1 to 16 of 16 in total 
Class	cellular component
Gene Ontology	integral to plasma membrane

Ratio	Regulation	description	
1.11083	down	Sodium- and chloride-dependent transporter XTRP3 (Solute carrier family 6 member 20) (Neurotransmitter transporter rB21A homolog). [Source:Uniprot/SWISSPROT;Acc:Q9NP91]	
1.15279	up	Podocalyxin-like protein 2 precursor (Endoglycan). [Source:Uniprot/SWISSPROT;Acc:Q9NZ53]	
1.30142	down	Fibroblast growth factor receptor 3 precursor (EC 2.7.10.1) (FGFR-3) (CD333 antigen). [Source:Uniprot/SWISSPROT;Acc:P22607]	
1.30802	down	Canalicular multispecific organic anion transporter 2 (ATP-binding cassette sub-family C member 3) (Multidrug resistance-associated protein 3) (Multi-specific organic anion transporter-D) (MOAT-D). [Source:Uniprot/SWISSPROT;Acc:O15438]	
1.40552	down	Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) (Amino acid transporter ATB0+) (Solute carrier family 6 member 14). [Source:Uniprot/SWISSPROT;Acc:Q9UN76]	
1.42215	down	Sodium-dependent serotonin transporter (5HT transporter) (5HTT). [Source:Uniprot/SWISSPROT;Acc:P31645]	
1.47697	up	Nck-associated protein 1-like (Membrane-associated protein HEM-1) (Hematopoietic protein 1). [Source:Uniprot/SWISSPROT;Acc:P55160]	
1.58045	down	Peroxisomal biogenesis factor 3 (Peroxin-3) (Peroxisomal assembly protein PEX3). [Source:Uniprot/SWISSPROT;Acc:P56589]	
1.61987	up	Proteinase-activated receptor 1 precursor (PAR-1) (Thrombin receptor) (Coagulation factor II receptor). [Source:Uniprot/SWISSPROT;Acc:P25116]	
1.98149	up	CD40 ligand (CD40-L) (Tumor necrosis factor ligand superfamily member 5) (TNF-related activation protein) (TRAP) (T cell antigen Gp39) (CD154 antigen) [Contains: CD40 ligand, membrane form; CD40 ligand, soluble form]. [Source:Uniprot/SWISSPROT;Acc:P29965]	
2.8521	up	transient receptor potential cation channel, subfamily M, member 1 [Source:RefSeq_peptide;Acc:NP_002411]	
2.88235	down	Anion exchange protein 3 (Neuronal band 3-like protein) (Solute carrier family 4 member 3) (Cardiac/brain band 3-like protein) (CAE3/BAE3). [Source:Uniprot/SWISSPROT;Acc:P48751]	
3.48558	up	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HEK-2) (Tyrosine-protein kinase TYRO6). [Source:Uniprot/SWISSPROT;Acc:P54753]	
4.03725	up	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon). [Source:Uniprot/SWISSPROT;Acc:P23469]	
4.55371	up	Parathyroid hormone/parathyroid hormone-related peptide receptor precursor (PTH/PTHr receptor) (PTH/PTHrP type I receptor). [Source:Uniprot/SWISSPROT;Acc:Q03431]	
4.62042	down	Leukocyte antigen CD37 (Tetraspanin-26) (Tspan-26). [Source:Uniprot/SWISSPROT;Acc:P11049]	

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells. 
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component. 
- The Gene Ontology terms as linked to the specific gene.
- http://analysis.yellowcouch.org/