Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes


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Ratio Regulation description Class Gene Ontology Gene Accession Minimum Ratio Maximum Ratio
Results: HTML CSV LaTeX Showing element 1 to 20 of 20 in total 
Class	biological process
Gene Ontology	G-protein coupled receptor protein signaling pathway

Ratio	Regulation	description	
1.07618	up	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2) (Renal carcinoma antigen NY-REN-20). [Source:Uniprot/SWISSPROT;Acc:Q15696]	
1.13007	up	Zinc finger protein 219. [Source:Uniprot/SWISSPROT;Acc:Q9P2Y4]	
1.16393	up	olfactory receptor, family 5, subfamily K, member 4 [Source:RefSeq_peptide;Acc:NP_001005517]	
1.19117	up	Ras-related GTP-binding protein D (Rag D). [Source:Uniprot/SWISSPROT;Acc:Q9NQL2]	
1.27461	down	Homeobox protein Hox-D3 (Hox-4A). [Source:Uniprot/SWISSPROT;Acc:P31249]	
1.351	down	TBK1 binding protein 1 [Source:RefSeq_peptide;Acc:NP_055541]	
1.36911	down	Orexigenic neuropeptide QRFP receptor (G-protein coupled receptor 103) (SP9155) (AQ27). [Source:Uniprot/SWISSPROT;Acc:Q96P65]	
1.40749	up	collagen, type XXVII, alpha 1 [Source:RefSeq_peptide;Acc:NP_116277]	
1.51342	down	Beta-defensin 2 precursor (BD-2) (hBD-2) (Defensin, beta 2) (Skin- antimicrobial peptide 1) (SAP1). [Source:Uniprot/SWISSPROT;Acc:O15263]	
1.61987	up	Proteinase-activated receptor 1 precursor (PAR-1) (Thrombin receptor) (Coagulation factor II receptor). [Source:Uniprot/SWISSPROT;Acc:P25116]	
1.6384	up	Olfactory receptor 6S1. [Source:Uniprot/SWISSPROT;Acc:Q8NH40]	
1.66123	up	KRAB-A domain containing 1 (KRBA1), mRNA [Source:RefSeq_dna;Acc:NM_032534]	
1.83601	up	coiled-coil domain containing 90A [Source:RefSeq_peptide;Acc:NP_001026883]	
1.93863	up	Olfactory receptor 2B2 (Olfactory receptor 6-1) (OR6-1) (Hs6M1-10). [Source:Uniprot/SWISSPROT;Acc:Q9GZK3]	
2.44552	down	Guanine nucleotide-binding protein alpha-14 subunit (G-protein alpha subunit 14). [Source:Uniprot/SWISSPROT;Acc:O95837]	
2.86538	up	Olfactory receptor 1J2 (Olfactory receptor OR9-19) (OST044) (HSA5) (HTPCRX15). [Source:Uniprot/SWISSPROT;Acc:Q8NGS2]	
3.52215	down	Olfactory receptor 4L1 (Olfactory receptor OR14-28). [Source:Uniprot/SWISSPROT;Acc:Q8NH43]	
3.54799	down	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta 2 (Transducin beta chain 2) (G protein beta 2 subunit). [Source:Uniprot/SWISSPROT;Acc:P62879]	
5.23046	down	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (EC 2.7.1.153) (PI3-kinase p110 subunit gamma) (PtdIns-3- kinase subunit p110) (PI3K) (PI3Kgamma) (p120-PI3K). [Source:Uniprot/SWISSPROT;Acc:P48736]	
7.45006	down	MAP7 domain containing 1 [Source:RefSeq_peptide;Acc:NP_060537]	

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells. 
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component. 
- The Gene Ontology terms as linked to the specific gene.
- http://analysis.yellowcouch.org/