Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Ratio Regulation description Class Gene Ontology Gene Accession Minimum Ratio Maximum Ratio

Results: HTML CSV LaTeX

Showing element 551 to 600 of 2667 in total


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\begin{longtable}{|c|c|c|c|c|}
\hline
\parbox{\wcA}{\vspace{3pt}\noindent
Ratio\vspace{3pt}}&\parbox{\wcB}{\vspace{3pt}\noindent
Regulation\vspace{3pt}}&\parbox{\wcC}{\vspace{3pt}\noindent
description\vspace{3pt}}&\parbox{\wcD}{\vspace{3pt}\noindent
Class\vspace{3pt}}&\parbox{\wcE}{\vspace{3pt}\noindent
Gene Ontology\vspace{3pt}}\\
\hline
\hline
\multirow{8}{*}{\parbox{\wcA}{\vspace{3pt}\noindent
1.25147\vspace{3pt}}}&\multirow{8}{*}{\parbox{\wcB}{\vspace{3pt}\noindent
up\vspace{3pt}}}&\multirow{8}{*}{\parbox{\wcC}{\vspace{3pt}\noindent
T-lymphocyte activation antigen CD86 precursor (Activation B7-2 antigen) (CTLA-4 counter-receptor B7.2) (B70) (FUN-1) (BU63). \vspace{3pt}}}&\multirow{2}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
biological process\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
T cell activation\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
T cell proliferation\vspace{3pt}}\\\cline{4-5}
&&&\multirow{3}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
cellular component\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
external side of plasma membrane\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
integral to membrane\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
plasma membrane\vspace{3pt}}\\\cline{4-5}
&&&\multirow{3}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
molecular function\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
coreceptor activity\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
protein binding\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
transcriptional activator activity\vspace{3pt}}\\\hline
\multirow{9}{*}{\parbox{\wcA}{\vspace{3pt}\noindent
1.25205\vspace{3pt}}}&\multirow{9}{*}{\parbox{\wcB}{\vspace{3pt}\noindent
down\vspace{3pt}}}&\multirow{9}{*}{\parbox{\wcC}{\vspace{3pt}\noindent
Protein CWC15 homolog. \vspace{3pt}}}&\multirow{3}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
biological process\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
nuclear mRNA splicing, via spliceosome\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
RNA splicing\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
SRP-dependent cotranslational protein targeting to membrane\vspace{3pt}}\\\cline{4-5}
&&&\multirow{3}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
cellular component\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
membrane\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
nucleus\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
spliceosome\vspace{3pt}}\\\cline{4-5}
&&&\multirow{3}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
molecular function\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
7S RNA binding\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
GTP binding\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
RNA binding\vspace{3pt}}\\\hline
\multirow{6}{*}{\parbox{\wcA}{\vspace{3pt}\noindent
1.25729\vspace{3pt}}}&\multirow{33}{*}{\parbox{\wcB}{\vspace{3pt}\noindent
up\vspace{3pt}}}&\multirow{6}{*}{\parbox{\wcC}{\vspace{3pt}\noindent
Dehydrogenase/reductase SDR family member 1 (EC 1.1.-.-). \vspace{3pt}}}&\multirow{2}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
biological process\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
enterobactin biosynthetic process\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
metabolic process\vspace{3pt}}\\\cline{4-5}
&&&\multirow{2}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
cellular component\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
endoplasmic reticulum\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
mitochondrial inner membrane\vspace{3pt}}\\\cline{4-5}
&&&\multirow{2}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
molecular function\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase activity\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
oxidoreductase activity\vspace{3pt}}\\\cline{1-1}\cline{3-5}
\multirow{27}{*}{\parbox{\wcA}{\vspace{3pt}\noindent
1.25808\vspace{3pt}}}&&\multirow{27}{*}{\parbox{\wcC}{\vspace{3pt}\noindent
Chromodomain-helicase-DNA-binding protein 7 (EC 3.6.1.-) (ATP- dependent helicase CHD7) (CHD-7). \vspace{3pt}}}&\multirow{19}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
biological process\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
adult heart development\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
adult walking behavior\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
blood vessel development\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
camera-type eye development\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
chromatin assembly or disassembly\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
chromatin modification\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
circulation\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
embryonic hindlimb morphogenesis\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
female genitalia development\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
heart morphogenesis\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
in utero embryonic development\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
inner ear morphogenesis\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
locomotory behavior\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
nose development\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
palate development\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
positive regulation of body size\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
regulation of transcription, DNA-dependent\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
sensory perception of sound\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
transcription\vspace{3pt}}\\\cline{4-5}
&&&\multirow{2}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
cellular component\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
chromatin\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
nucleus\vspace{3pt}}\\\cline{4-5}
&&&\multirow{6}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
molecular function\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
ATP binding\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
chromatin binding\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
DNA binding\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
helicase activity\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
hydrolase activity\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
nucleic acid binding\vspace{3pt}}\\\hline
nd{longtable}

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.

 - The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells. 

 - The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component. 

 - The Gene Ontology terms as linked to the specific gene.

 - Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray

 - Accession is the GO accession key. 

 - Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.

 - Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.

- http://analysis.yellowcouch.org/