Scientific

MK5 Microarray Data


Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes


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Ratio Regulation description Class Gene Ontology Gene Accession Minimum Ratio Maximum Ratio
Results: HTML CSV LaTeX Showing element 1 to 8 of 8 in total
Class	cellular component
Gene Ontology cytoskeleton
Ratio Regulation description 1.10233 up GAS2-like protein 1 (Growth arrest-specific 2-like 1) (GAS2-related protein on chromosome 22) (GAR22 protein). [Source:Uniprot/SWISSPROT;Acc:Q99501] 1.29151 up CLIP-associating protein 2 (Cytoplasmic linker-associated protein 2) (hOrbit2). [Source:Uniprot/SWISSPROT;Acc:O75122] 1.36997 up Rho GTPase-activating protein 24 (Rho-type GTPase-activating protein 24) (Filamin-A-associated RhoGAP) (FilGAP) (p73RhoGAP) (RhoGAP of 73 kDa) (RAC1- and CDC42-specific GTPase-activating protein of 72 kDa) (RC-GAP72) (Sarcoma antigen NY-SAR-88). [Source:Uniprot/SWISSPROT;Acc:Q8N264] 1.37801 up Glycerophosphodiester phosphodiesterase domain-containing protein 2 (EC 3.1.-.-) (Glycerophosphodiester phosphodiesterase 3) (Osteoblast differentiation promoting factor). [Source:Uniprot/SWISSPROT;Acc:Q9HCC8] 2.95579 up Protein phosphatase Slingshot homolog 3 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-3L) (hSSH-3L). [Source:Uniprot/SWISSPROT;Acc:Q8TE77] 4.50619 down Engulfment and cell motility protein 2 (CED-12 homolog A) (hCED-12A). [Source:Uniprot/SWISSPROT;Acc:Q96JJ3] 5.81102 up PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (PDZ-LIM protein). [Source:Uniprot/SWISSPROT;Acc:Q96JY6] 5.84607 down Tubulin-specific chaperone E (Tubulin-folding cofactor E). [Source:Uniprot/SWISSPROT;Acc:Q15813] Legend: - The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration. - The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells. - The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component. - The Gene Ontology terms as linked to the specific gene.

- http://analysis.yellowcouch.org/