Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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Ratio Regulation description Class Gene Ontology Gene Accession Minimum Ratio Maximum Ratio

Results: HTML CSV LaTeX

Showing element 1 to 15 of 15 in total

Class: molecular function
Gene Ontology: sequence-specific DNA binding

\def\wcA{0.25\textwidth}
\def\wcB{0.25\textwidth}
\def\wcC{0.25\textwidth}
\begin{longtable}{|c|c|c|}
\hline
\parbox{\wcA}{\vspace{3pt}\noindent
Ratio\vspace{3pt}}&\parbox{\wcB}{\vspace{3pt}\noindent
Regulation\vspace{3pt}}&\parbox{\wcC}{\vspace{3pt}\noindent
description\vspace{3pt}}\\
\hline
\hline
\parbox{\wcA}{\vspace{3pt}\noindent
1.10889\vspace{3pt}}&\parbox{\wcB}{\vspace{3pt}\noindent
up\vspace{3pt}}&\parbox{\wcC}{\vspace{3pt}\noindent
Nuclear receptor-binding factor 2 (NRBF-2) (Comodulator of PPAR and RXR). \vspace{3pt}}\\\hline
\parbox{\wcA}{\vspace{3pt}\noindent
1.27461\vspace{3pt}}&\multirow{2}{*}{\parbox{\wcB}{\vspace{3pt}\noindent
down\vspace{3pt}}}&\parbox{\wcC}{\vspace{3pt}\noindent
Homeobox protein Hox-D3 (Hox-4A). \vspace{3pt}}\\\cline{1-1}\cline{3-3}
\parbox{\wcA}{\vspace{3pt}\noindent
1.28356\vspace{3pt}}&&\parbox{\wcC}{\vspace{3pt}\noindent
T-box transcription factor TBX2 (T-box protein 2). \vspace{3pt}}\\\hline
\parbox{\wcA}{\vspace{3pt}\noindent
1.30407\vspace{3pt}}&\multirow{5}{*}{\parbox{\wcB}{\vspace{3pt}\noindent
up\vspace{3pt}}}&\parbox{\wcC}{\vspace{3pt}\noindent
Homeobox protein Nkx-2.8 (Homeobox protein NK-2 homolog H). \vspace{3pt}}\\\cline{1-1}\cline{3-3}
\parbox{\wcA}{\vspace{3pt}\noindent
1.33465\vspace{3pt}}&&\parbox{\wcC}{\vspace{3pt}\noindent
T-box transcription factor TBX5 (T-box protein 5). \vspace{3pt}}\\\cline{1-1}\cline{3-3}
\parbox{\wcA}{\vspace{3pt}\noindent
1.45624\vspace{3pt}}&&\parbox{\wcC}{\vspace{3pt}\noindent
Transcription factor NF-E2 45 kDa subunit (Nuclear factor, erythroid- derived 2 45 kDa subunit) (p45 NF-E2) (Leucine zipper protein NF-E2). \vspace{3pt}}\\\cline{1-1}\cline{3-3}
\parbox{\wcA}{\vspace{3pt}\noindent
1.50206\vspace{3pt}}&&\parbox{\wcC}{\vspace{3pt}\noindent
LAG1 longevity assurance homolog 4. \vspace{3pt}}\\\cline{1-1}\cline{3-3}
\parbox{\wcA}{\vspace{3pt}\noindent
1.57088\vspace{3pt}}&&\parbox{\wcC}{\vspace{3pt}\noindent
Forkhead box protein P2 (CAG repeat protein 44) (Trinucleotide repeat- containing gene 10 protein). \vspace{3pt}}\\\hline
\parbox{\wcA}{\vspace{3pt}\noindent
1.98137\vspace{3pt}}&\parbox{\wcB}{\vspace{3pt}\noindent
down\vspace{3pt}}&\parbox{\wcC}{\vspace{3pt}\noindent
Nuclear receptor ROR-alpha (Retinoid-related orphan receptor-alpha) (Nuclear receptor RZR-alpha). \vspace{3pt}}\\\hline
\parbox{\wcA}{\vspace{3pt}\noindent
2.10428\vspace{3pt}}&\parbox{\wcB}{\vspace{3pt}\noindent
up\vspace{3pt}}&\parbox{\wcC}{\vspace{3pt}\noindent
Transcription factor AP-1 (Activator protein 1) (AP1) (Proto-oncogene c-jun) (V-jun avian sarcoma virus 17 oncogene homolog) (p39). \vspace{3pt}}\\\hline
\parbox{\wcA}{\vspace{3pt}\noindent
3.29064\vspace{3pt}}&\multirow{2}{*}{\parbox{\wcB}{\vspace{3pt}\noindent
down\vspace{3pt}}}&\parbox{\wcC}{\vspace{3pt}\noindent
Transcription factor GATA-6 (GATA-binding factor 6). \vspace{3pt}}\\\cline{1-1}\cline{3-3}
\parbox{\wcA}{\vspace{3pt}\noindent
3.48313\vspace{3pt}}&&\parbox{\wcC}{\vspace{3pt}\noindent
Homeobox protein TGIF2 (5'-TG-3'-interacting factor 2) (TGFB-induced factor 2) (TGF(beta)-induced transcription factor 2). \vspace{3pt}}\\\hline
\parbox{\wcA}{\vspace{3pt}\noindent
3.70292\vspace{3pt}}&\multirow{2}{*}{\parbox{\wcB}{\vspace{3pt}\noindent
up\vspace{3pt}}}&\parbox{\wcC}{\vspace{3pt}\noindent
Homeobox protein SIX4 (Sine oculis homeobox homolog 4). \vspace{3pt}}\\\cline{1-1}\cline{3-3}
\parbox{\wcA}{\vspace{3pt}\noindent
4.04651\vspace{3pt}}&&\parbox{\wcC}{\vspace{3pt}\noindent
Sad1/unc-84-like protein 2 (Rab5-interacting protein) (Rab5IP). \vspace{3pt}}\\\hline
\parbox{\wcA}{\vspace{3pt}\noindent
4.4149\vspace{3pt}}&\parbox{\wcB}{\vspace{3pt}\noindent
down\vspace{3pt}}&\parbox{\wcC}{\vspace{3pt}\noindent
X box-binding protein 1 (XBP-1) (Tax-responsive element-binding protein 5). \vspace{3pt}}\\\hline
nd{longtable}

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.

 - The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells. 

 - The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component. 

 - The Gene Ontology terms as linked to the specific gene.

 - Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray

 - Accession is the GO accession key. 

 - Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.

 - Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.

- http://analysis.yellowcouch.org/