Scientific

MK5 Microarray Data


Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes


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Ratio Regulation description Class Gene Ontology Gene Accession Minimum Ratio Maximum Ratio
Results: HTML CSV LaTeX Showing element 1 to 6 of 6 in total
Class	biological process
Gene Ontology positive regulation of transcription
Ratio Regulation description 1.10867 up Somatoliberin precursor (Growth hormone-releasing factor) (GRF) (Growth hormone-releasing hormone) (GHRH) (Somatocrinin) (Somatorelin) (Sermorelin). [Source:Uniprot/SWISSPROT;Acc:P01286] 1.25147 up T-lymphocyte activation antigen CD86 precursor (Activation B7-2 antigen) (CTLA-4 counter-receptor B7.2) (B70) (FUN-1) (BU63). [Source:Uniprot/SWISSPROT;Acc:P42081] 1.45635 up Cyclin-A2 (Cyclin-A). [Source:Uniprot/SWISSPROT;Acc:P20248] 2.83611 down SERTA domain-containing protein 3 (Replication protein-binding trans- activator) (RPA-binding trans-activator). [Source:Uniprot/SWISSPROT;Acc:Q9UJW9] 3.29064 down Transcription factor GATA-6 (GATA-binding factor 6). [Source:Uniprot/SWISSPROT;Acc:Q92908] 3.70292 up Homeobox protein SIX4 (Sine oculis homeobox homolog 4). [Source:Uniprot/SWISSPROT;Acc:Q9UIU6] Legend: - The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration. - The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells. - The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component. - The Gene Ontology terms as linked to the specific gene.

- http://analysis.yellowcouch.org/