Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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Ratio Regulation description Class Gene Ontology Gene Accession Minimum Ratio Maximum Ratio

Results: HTML CSV LaTeX

Showing element 1 to 29 of 29 in total

Class	biological process
Gene Ontology	transcription

Ratio	Regulation	description	
1.10889	up	Nuclear receptor-binding factor 2 (NRBF-2) (Comodulator of PPAR and RXR). [Source:Uniprot/SWISSPROT;Acc:Q96F24]	
1.1243	down	Zinc finger protein basonuclin-2. [Source:Uniprot/SWISSPROT;Acc:Q6ZN30]	
1.22576	up	Methyl-CpG-binding domain protein 1 (Methyl-CpG-binding protein MBD1) (Protein containing methyl-CpG-binding domain 1). [Source:Uniprot/SWISSPROT;Acc:Q9UIS9]	
1.25808	up	Chromodomain-helicase-DNA-binding protein 7 (EC 3.6.1.-) (ATP- dependent helicase CHD7) (CHD-7). [Source:Uniprot/SWISSPROT;Acc:Q9P2D1]	
1.28356	down	T-box transcription factor TBX2 (T-box protein 2). [Source:Uniprot/SWISSPROT;Acc:Q13207]	
1.33465	up	T-box transcription factor TBX5 (T-box protein 5). [Source:Uniprot/SWISSPROT;Acc:Q99593]	
1.44789	up	POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1) (OCT-binding factor 1) (BOB-1) (OCA-B). [Source:Uniprot/SWISSPROT;Acc:Q16633]	
1.57088	up	Forkhead box protein P2 (CAG repeat protein 44) (Trinucleotide repeat- containing gene 10 protein). [Source:Uniprot/SWISSPROT;Acc:O15409]	
1.59188	up	Zinc finger protein 384 (Nuclear matrix transcription factor 4) (Nuclear matrix protein 4) (CAG repeat protein 1) (CAS-interacting zinc finger protein) (Trinucleotide repeat-containing gene 1 protein). [Source:Uniprot/SWISSPROT;Acc:Q8TF68]	
1.60746	down	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein). [Source:Uniprot/SWISSPROT;Acc:Q8TD26]	
1.78439	up	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta). [Source:Uniprot/SWISSPROT;Acc:Q14839]	
1.86204	down	Zinc finger and SCAN domain-containing protein 4 (Zinc finger protein 494). [Source:Uniprot/SWISSPROT;Acc:Q8NAM6]	
1.89168	down	Zinc finger protein 202 (Zinc finger protein with KRAB and SCAN domains 10). [Source:Uniprot/SWISSPROT;Acc:O95125]	
1.93995	up	Zinc finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2). [Source:Uniprot/SWISSPROT;Acc:Q92785]	
1.98137	down	Nuclear receptor ROR-alpha (Retinoid-related orphan receptor-alpha) (Nuclear receptor RZR-alpha). [Source:Uniprot/SWISSPROT;Acc:P35398]	
2.31039	up	STAGA complex 65 subunit gamma (STAF65gamma) (SPTF-associated factor 65 gamma) (Suppressor of Ty 7-like) (Adenocarcinoma antigen ART1). [Source:Uniprot/SWISSPROT;Acc:O94864]	
2.58329	down	Myelin transcription factor 1-like protein (MyT1L protein) (MyT1-L). [Source:Uniprot/SWISSPROT;Acc:Q9UL68]	
2.83611	down	SERTA domain-containing protein 3 (Replication protein-binding trans- activator) (RPA-binding trans-activator). [Source:Uniprot/SWISSPROT;Acc:Q9UJW9]	
2.86298	up	T-brain-1 protein (T-box brain protein 1) (TBR-1) (TES-56). [Source:Uniprot/SWISSPROT;Acc:Q16650]	
3.27919	down	Calsenilin (Kv channel-interacting protein 3) (KChIP3) (A-type potassium channel modulatory protein 3) (DRE-antagonist modulator) (DREAM). [Source:Uniprot/SWISSPROT;Acc:Q9Y2W7]	
3.29064	down	Transcription factor GATA-6 (GATA-binding factor 6). [Source:Uniprot/SWISSPROT;Acc:Q92908]	
3.35536	up	RNA polymerase-associated protein RTF1 homolog. [Source:Uniprot/SWISSPROT;Acc:Q92541]	
3.81736	up	Transcription factor E2F3 (E2F-3). [Source:Uniprot/SWISSPROT;Acc:O00716]	
3.83977	down	AT-hook-containing transcription factor 1 (Embryonic large molecule derived from yolk sac). [Source:Uniprot/SWISSPROT;Acc:Q8WYP5]	
4.4149	down	X box-binding protein 1 (XBP-1) (Tax-responsive element-binding protein 5). [Source:Uniprot/SWISSPROT;Acc:P17861]	
4.49282	down	Enhancer of polycomb homolog 1. [Source:Uniprot/SWISSPROT;Acc:Q9H2F5]	
4.55177	up	Transcription factor SOX-14. [Source:Uniprot/SWISSPROT;Acc:O95416]	
6.3909	down	Protein Jade-1 (PHD finger protein 17). [Source:Uniprot/SWISSPROT;Acc:Q6IE81]	
6.56408	down	DNA-directed RNA polymerase III subunit RPC8 (RNA polymerase III subunit C8) (DNA-directed RNA polymerase III subunit H) (DNA-directed RNA polymerase III subunit 22.9 kDa polypeptide). [Source:Uniprot/SWISSPROT;Acc:Q9Y535]	

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells. 
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component. 
- The Gene Ontology terms as linked to the specific gene.

- http://analysis.yellowcouch.org/