MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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Ratio	Regulation	description	Class	Gene Ontology	Gene	Accession	Maximum Ratio	Minimum Ratio

Results: HTML CSV LaTeX

Showing element 1 to 19 of 19 in total

Regulation  : down
Class  : molecular function
Gene Ontology  : metal ion binding

Ratio	description
1.1243	Zinc finger protein basonuclin-2. [Uniprot/SWISSPROT;Acc:Q6ZN30]
1.18096	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II). [Uniprot/SWISSPROT;Acc:P35354]
1.23783	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein). [Uniprot/SWISSPROT;Acc:Q8WZ64]
1.25113	Zinc finger protein OZF (Only zinc finger protein) (Zinc finger protein 146). [Uniprot/SWISSPROT;Acc:Q15072]
1.28805	ADAM metallopeptidase with thrombospondin type 1 motif, 7 preproprotein [RefSeq_peptide;Acc:NP_055087]
1.30869	E3 ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein) (RING finger protein 196). [Uniprot/SWISSPROT;Acc:Q96EP1]
1.31489	Tripartite motif-containing protein 58 (Protein BIA2). [Uniprot/SWISSPROT;Acc:Q8NG06]
1.43351	Carboxypeptidase A2 precursor (EC 3.4.17.15). [Uniprot/SWISSPROT;Acc:P48052]
1.48389	Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa nucleoporin). [Uniprot/SWISSPROT;Acc:P49790]
1.76994	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha). [Uniprot/SWISSPROT;Acc:O43184]
1.86204	Zinc finger and SCAN domain-containing protein 4 (Zinc finger protein 494). [Uniprot/SWISSPROT;Acc:Q8NAM6]
1.89168	Zinc finger protein 202 (Zinc finger protein with KRAB and SCAN domains 10). [Uniprot/SWISSPROT;Acc:O95125]
1.98137	Nuclear receptor ROR-alpha (Retinoid-related orphan receptor-alpha) (Nuclear receptor RZR-alpha). [Uniprot/SWISSPROT;Acc:P35398]
2.31699	Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform (EC 3.1.3.16) (PP2A-beta). [Uniprot/SWISSPROT;Acc:P62714]
2.58329	Myelin transcription factor 1-like protein (MyT1L protein) (MyT1-L). [Uniprot/SWISSPROT;Acc:Q9UL68]
2.93895	TRAF family member-associated NF-kappa-B activator (TRAF-interacting protein) (I-TRAF). [Uniprot/SWISSPROT;Acc:Q92844]
3.29064	Transcription factor GATA-6 (GATA-binding factor 6). [Uniprot/SWISSPROT;Acc:Q92908]
5.61927	RING finger protein 170 (Putative LAG1-interacting protein). [Uniprot/SWISSPROT;Acc:Q96K19]
6.3909	Protein Jade-1 (PHD finger protein 17). [Uniprot/SWISSPROT;Acc:Q6IE81]

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.