Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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Ratio Regulation description Class Gene Gene Ontology Accession Minimum Ratio Maximum Ratio

Results: HTML CSV LaTeX

Showing element 51 to 100 of 2667 in total

Ratio	Regulation	description	Class	Gene Ontology	
1.11519	up	eukaryotic translation initiation factor 4E family member 1B (EIF4E1B), mRNA [Source:RefSeq_dna;Acc:NM_001099408]	molecular function	RNA binding	
1.11519	up	eukaryotic translation initiation factor 4E family member 1B (EIF4E1B), mRNA [Source:RefSeq_dna;Acc:NM_001099408]	molecular function	translation initiation factor activity	
1.11956	down	Protein RER1. [Source:Uniprot/SWISSPROT;Acc:O15258]	biological process	retrograde vesicle-mediated transport, Golgi to ER	
1.11956	down	Protein RER1. [Source:Uniprot/SWISSPROT;Acc:O15258]	cellular component	Golgi apparatus	
1.11956	down	Protein RER1. [Source:Uniprot/SWISSPROT;Acc:O15258]	cellular component	integral to Golgi membrane	
1.11956	down	Protein RER1. [Source:Uniprot/SWISSPROT;Acc:O15258]	cellular component	integral to membrane	
1.11956	down	Protein RER1. [Source:Uniprot/SWISSPROT;Acc:O15258]	cellular component	membrane	
1.11956	down	Protein RER1. [Source:Uniprot/SWISSPROT;Acc:O15258]	molecular function	molecular_function	
1.12417	up	Protein CutA precursor (Brain acetylcholinesterase putative membrane anchor) (Acetylcholinesterase-associated protein). [Source:Uniprot/SWISSPROT;Acc:O60888]	biological process	protein homooligomerization	
1.12417	up	Protein CutA precursor (Brain acetylcholinesterase putative membrane anchor) (Acetylcholinesterase-associated protein). [Source:Uniprot/SWISSPROT;Acc:O60888]	biological process	protein localization	
1.12417	up	Protein CutA precursor (Brain acetylcholinesterase putative membrane anchor) (Acetylcholinesterase-associated protein). [Source:Uniprot/SWISSPROT;Acc:O60888]	biological process	response to metal ion	
1.12417	up	Protein CutA precursor (Brain acetylcholinesterase putative membrane anchor) (Acetylcholinesterase-associated protein). [Source:Uniprot/SWISSPROT;Acc:O60888]	cellular component	membrane	
1.12417	up	Protein CutA precursor (Brain acetylcholinesterase putative membrane anchor) (Acetylcholinesterase-associated protein). [Source:Uniprot/SWISSPROT;Acc:O60888]	molecular function	enzyme binding	
1.12417	up	Protein CutA precursor (Brain acetylcholinesterase putative membrane anchor) (Acetylcholinesterase-associated protein). [Source:Uniprot/SWISSPROT;Acc:O60888]	molecular function	protein heterodimerization activity	
1.12417	up	Protein CutA precursor (Brain acetylcholinesterase putative membrane anchor) (Acetylcholinesterase-associated protein). [Source:Uniprot/SWISSPROT;Acc:O60888]	molecular function	retinoic acid receptor binding	
1.12417	up	Protein CutA precursor (Brain acetylcholinesterase putative membrane anchor) (Acetylcholinesterase-associated protein). [Source:Uniprot/SWISSPROT;Acc:O60888]	molecular function	retinoid-X receptor activity	
1.12417	up	Protein CutA precursor (Brain acetylcholinesterase putative membrane anchor) (Acetylcholinesterase-associated protein). [Source:Uniprot/SWISSPROT;Acc:O60888]	molecular function	thyroid hormone receptor binding	
1.12417	up	Protein CutA precursor (Brain acetylcholinesterase putative membrane anchor) (Acetylcholinesterase-associated protein). [Source:Uniprot/SWISSPROT;Acc:O60888]	molecular function	thyroid hormone receptor coactivator activity	
1.12417	up	Protein CutA precursor (Brain acetylcholinesterase putative membrane anchor) (Acetylcholinesterase-associated protein). [Source:Uniprot/SWISSPROT;Acc:O60888]	molecular function	vitamin D receptor binding	
1.1243	down	Zinc finger protein basonuclin-2. [Source:Uniprot/SWISSPROT;Acc:Q6ZN30]	biological process	regulation of transcription, DNA-dependent	
1.1243	down	Zinc finger protein basonuclin-2. [Source:Uniprot/SWISSPROT;Acc:Q6ZN30]	biological process	transcription	
1.1243	down	Zinc finger protein basonuclin-2. [Source:Uniprot/SWISSPROT;Acc:Q6ZN30]	cellular component	intracellular	
1.1243	down	Zinc finger protein basonuclin-2. [Source:Uniprot/SWISSPROT;Acc:Q6ZN30]	cellular component	nucleus	
1.1243	down	Zinc finger protein basonuclin-2. [Source:Uniprot/SWISSPROT;Acc:Q6ZN30]	molecular function	DNA binding	
1.1243	down	Zinc finger protein basonuclin-2. [Source:Uniprot/SWISSPROT;Acc:Q6ZN30]	molecular function	metal ion binding	
1.1243	down	Zinc finger protein basonuclin-2. [Source:Uniprot/SWISSPROT;Acc:Q6ZN30]	molecular function	nucleic acid binding	
1.1243	down	Zinc finger protein basonuclin-2. [Source:Uniprot/SWISSPROT;Acc:Q6ZN30]	molecular function	zinc ion binding	
1.13007	up	Zinc finger protein 219. [Source:Uniprot/SWISSPROT;Acc:Q9P2Y4]	biological process	anion transport	
1.13007	up	Zinc finger protein 219. [Source:Uniprot/SWISSPROT;Acc:Q9P2Y4]	biological process	G-protein coupled receptor protein signaling pathway	
1.13007	up	Zinc finger protein 219. [Source:Uniprot/SWISSPROT;Acc:Q9P2Y4]	biological process	regulation of transcription, DNA-dependent	
1.13007	up	Zinc finger protein 219. [Source:Uniprot/SWISSPROT;Acc:Q9P2Y4]	cellular component	integral to membrane	
1.13007	up	Zinc finger protein 219. [Source:Uniprot/SWISSPROT;Acc:Q9P2Y4]	cellular component	intracellular	
1.13007	up	Zinc finger protein 219. [Source:Uniprot/SWISSPROT;Acc:Q9P2Y4]	cellular component	membrane	
1.13007	up	Zinc finger protein 219. [Source:Uniprot/SWISSPROT;Acc:Q9P2Y4]	cellular component	nucleus	
1.13007	up	Zinc finger protein 219. [Source:Uniprot/SWISSPROT;Acc:Q9P2Y4]	molecular function	histamine receptor activity	
1.13007	up	Zinc finger protein 219. [Source:Uniprot/SWISSPROT;Acc:Q9P2Y4]	molecular function	inorganic anion exchanger activity	
1.13007	up	Zinc finger protein 219. [Source:Uniprot/SWISSPROT;Acc:Q9P2Y4]	molecular function	metal ion binding	
1.13007	up	Zinc finger protein 219. [Source:Uniprot/SWISSPROT;Acc:Q9P2Y4]	molecular function	nucleic acid binding	
1.13007	up	Zinc finger protein 219. [Source:Uniprot/SWISSPROT;Acc:Q9P2Y4]	molecular function	transcription factor activity	
1.13007	up	Zinc finger protein 219. [Source:Uniprot/SWISSPROT;Acc:Q9P2Y4]	molecular function	zinc ion binding	
1.13541	down	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2). [Source:Uniprot/SWISSPROT;Acc:Q99435]	biological process	blood coagulation	
1.13541	down	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2). [Source:Uniprot/SWISSPROT;Acc:Q99435]	biological process	cell adhesion	
1.13541	down	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2). [Source:Uniprot/SWISSPROT;Acc:Q99435]	biological process	regulation of growth	
1.13541	down	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2). [Source:Uniprot/SWISSPROT;Acc:Q99435]	cellular component	extracellular region	
1.13541	down	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2). [Source:Uniprot/SWISSPROT;Acc:Q99435]	cellular component	membrane	
1.13541	down	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2). [Source:Uniprot/SWISSPROT;Acc:Q99435]	molecular function	calcium ion binding	
1.13541	down	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2). [Source:Uniprot/SWISSPROT;Acc:Q99435]	molecular function	protein binding	
1.13541	down	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2). [Source:Uniprot/SWISSPROT;Acc:Q99435]	molecular function	structural molecule activity	
1.13541	down	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2). [Source:Uniprot/SWISSPROT;Acc:Q99435]	molecular function	transmembrane receptor activity	
1.14311	down	14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1). [Source:Uniprot/SWISSPROT;Acc:P61981]	biological process	negative regulation of protein kinase activity	

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells. 
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component. 
- The Gene Ontology terms as linked to the specific gene.

- http://analysis.yellowcouch.org/