MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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description	Ratio	Regulation	Class	Gene	Gene Ontology	Accession	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 1451 to 1500 of 2667 in total

description	Ratio	Regulation	Class	Gene Ontology
Olfactory receptor 2B2 (Olfactory receptor 6-1) (OR6-1) (Hs6M1-10). [Uniprot/SWISSPROT;Acc:Q9GZK3]	1.93863	up	cellular component	membrane
			molecular function	olfactory receptor activity
				receptor activity
				rhodopsin-like receptor activity
Olfactory receptor 4L1 (Olfactory receptor OR14-28). [Uniprot/SWISSPROT;Acc:Q8NH43]	3.52215	down	biological process	G-protein coupled receptor protein signaling pathway
				response to stimulus
				sensory perception of smell
				signal transduction
			cellular component	integral to membrane
				membrane
			molecular function	melanocortin receptor activity
				olfactory receptor activity
				receptor activity
				rhodopsin-like receptor activity
Olfactory receptor 6S1. [Uniprot/SWISSPROT;Acc:Q8NH40]	1.6384	up	biological process	G-protein coupled receptor protein signaling pathway
				signal transduction
			cellular component	integral to membrane
				membrane
			molecular function	olfactory receptor activity
				receptor activity
				rhodopsin-like receptor activity
olfactory receptor, family 5, subfamily K, member 4 [RefSeq_peptide;Acc:NP_001005517]	1.16393		biological process	G-protein coupled receptor protein signaling pathway
			cellular component	integral to membrane
			molecular function	olfactory receptor activity
				rhodopsin-like receptor activity
oligonucleotide/oligosaccharide-binding fold containing 2B [RefSeq_peptide;Acc:NP_076973]	1.16173			nucleic acid binding
OMA1 homolog, zinc metallopeptidase [RefSeq_peptide;Acc:NP_660286]	2.4954		biological process	proteolysis
			cellular component	membrane
			molecular function	metalloendopeptidase activity
				metallopeptidase activity
				zinc ion binding
Opa-interacting protein 5. [Uniprot/SWISSPROT;Acc:O43482]	2.72371		biological process	cell communication
			cellular component	Cajal body
				cellular_component
				chromatin
				chromocenter
				nucleus
			molecular function	protein binding
Orexigenic neuropeptide QRFP receptor (G-protein coupled receptor 103) (SP9155) (AQ27). [Uniprot/SWISSPROT;Acc:Q96P65]	1.36911	down	biological process	G-protein coupled receptor protein signaling pathway
				signal transduction
			cellular component	integral to membrane
				membrane
			molecular function	bombesin receptor activity
				metabotropic glutamate, GABA-B-like receptor activity
				neuropeptide receptor activity
				neuropeptide Y receptor activity
				orexin receptor activity
				purinergic nucleotide receptor activity, G-protein coupled
				receptor activity
				rhodopsin-like receptor activity

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.