Scientific
MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis
These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.
Affected Genes

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Ratio Regulation description Gene Ontology Class Gene Accession Minimum Ratio Maximum Ratio
Results: HTML CSV LaTeX
Showing element 93 to 142 of 2667 in total
Ratio	Regulation	description	Gene Ontology	Class	
1.13541	down	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2). [Source:Uniprot/SWISSPROT;Acc:Q99435]	cell adhesion	biological process	
1.13541	down	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2). [Source:Uniprot/SWISSPROT;Acc:Q99435]	extracellular region	cellular component	
1.13541	down	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2). [Source:Uniprot/SWISSPROT;Acc:Q99435]	membrane	cellular component	
1.13541	down	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2). [Source:Uniprot/SWISSPROT;Acc:Q99435]	protein binding	molecular function	
1.13541	down	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2). [Source:Uniprot/SWISSPROT;Acc:Q99435]	regulation of growth	biological process	
1.13541	down	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2). [Source:Uniprot/SWISSPROT;Acc:Q99435]	structural molecule activity	molecular function	
1.13541	down	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2). [Source:Uniprot/SWISSPROT;Acc:Q99435]	transmembrane receptor activity	molecular function	
1.14311	down	14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1). [Source:Uniprot/SWISSPROT;Acc:P61981]	cytoplasm	cellular component	
1.14311	down	14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1). [Source:Uniprot/SWISSPROT;Acc:P61981]	insulin-like growth factor receptor binding	molecular function	
1.14311	down	14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1). [Source:Uniprot/SWISSPROT;Acc:P61981]	negative regulation of protein kinase activity	biological process	
1.14311	down	14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1). [Source:Uniprot/SWISSPROT;Acc:P61981]	protein domain specific binding	molecular function	
1.14311	down	14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1). [Source:Uniprot/SWISSPROT;Acc:P61981]	protein kinase C binding	molecular function	
1.14311	down	14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1). [Source:Uniprot/SWISSPROT;Acc:P61981]	protein kinase C inhibitor activity	molecular function	
1.14311	down	14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1). [Source:Uniprot/SWISSPROT;Acc:P61981]	protein targeting	biological process	
1.14311	down	14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1). [Source:Uniprot/SWISSPROT;Acc:P61981]	regulation of neuron differentiation	biological process	
1.14311	down	14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1). [Source:Uniprot/SWISSPROT;Acc:P61981]	regulation of signal transduction	biological process	
1.14311	down	14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1). [Source:Uniprot/SWISSPROT;Acc:P61981]	regulation of synaptic plasticity	biological process	
1.14915	up	Transmembrane emp24 domain-containing protein 1 precursor (Interleukin-1 receptor-like 1 ligand) (Putative T1/ST2 receptor- binding protein). [Source:Uniprot/SWISSPROT;Acc:Q13445]	cell-cell signaling	biological process	
1.14915	up	Transmembrane emp24 domain-containing protein 1 precursor (Interleukin-1 receptor-like 1 ligand) (Putative T1/ST2 receptor- binding protein). [Source:Uniprot/SWISSPROT;Acc:Q13445]	integral to membrane	cellular component	
1.14915	up	Transmembrane emp24 domain-containing protein 1 precursor (Interleukin-1 receptor-like 1 ligand) (Putative T1/ST2 receptor- binding protein). [Source:Uniprot/SWISSPROT;Acc:Q13445]	membrane	cellular component	
1.14915	up	Transmembrane emp24 domain-containing protein 1 precursor (Interleukin-1 receptor-like 1 ligand) (Putative T1/ST2 receptor- binding protein). [Source:Uniprot/SWISSPROT;Acc:Q13445]	receptor binding	molecular function	
1.14915	up	Transmembrane emp24 domain-containing protein 1 precursor (Interleukin-1 receptor-like 1 ligand) (Putative T1/ST2 receptor- binding protein). [Source:Uniprot/SWISSPROT;Acc:Q13445]	signal transduction	biological process	
1.14915	up	Transmembrane emp24 domain-containing protein 1 precursor (Interleukin-1 receptor-like 1 ligand) (Putative T1/ST2 receptor- binding protein). [Source:Uniprot/SWISSPROT;Acc:Q13445]	transport	biological process	
1.15279	up	Podocalyxin-like protein 2 precursor (Endoglycan). [Source:Uniprot/SWISSPROT;Acc:Q9NZ53]	cell adhesion	biological process	
1.15279	up	Podocalyxin-like protein 2 precursor (Endoglycan). [Source:Uniprot/SWISSPROT;Acc:Q9NZ53]	glycosaminoglycan binding	molecular function	
1.15279	up	Podocalyxin-like protein 2 precursor (Endoglycan). [Source:Uniprot/SWISSPROT;Acc:Q9NZ53]	integral to plasma membrane	cellular component	
1.15279	up	Podocalyxin-like protein 2 precursor (Endoglycan). [Source:Uniprot/SWISSPROT;Acc:Q9NZ53]	membrane	cellular component	
1.15279	up	Podocalyxin-like protein 2 precursor (Endoglycan). [Source:Uniprot/SWISSPROT;Acc:Q9NZ53]	protein binding	molecular function	
1.15279	up	Podocalyxin-like protein 2 precursor (Endoglycan). [Source:Uniprot/SWISSPROT;Acc:Q9NZ53]	structural molecule activity	molecular function	
1.15279	up	Podocalyxin-like protein 2 precursor (Endoglycan). [Source:Uniprot/SWISSPROT;Acc:Q9NZ53]	viral capsid	cellular component	
1.1611	down	Guanylin precursor (Guanylate cyclase activator 2A) (Guanylate cyclase-activating protein 1) (Gap-I) [Contains: HMW-guanylin; Guanylin]. [Source:Uniprot/SWISSPROT;Acc:Q02747]	electron carrier activity	molecular function	
1.1611	down	Guanylin precursor (Guanylate cyclase activator 2A) (Guanylate cyclase-activating protein 1) (Gap-I) [Contains: HMW-guanylin; Guanylin]. [Source:Uniprot/SWISSPROT;Acc:Q02747]	electron transport	biological process	
1.1611	down	Guanylin precursor (Guanylate cyclase activator 2A) (Guanylate cyclase-activating protein 1) (Gap-I) [Contains: HMW-guanylin; Guanylin]. [Source:Uniprot/SWISSPROT;Acc:Q02747]	enzyme activator activity	molecular function	
1.1611	down	Guanylin precursor (Guanylate cyclase activator 2A) (Guanylate cyclase-activating protein 1) (Gap-I) [Contains: HMW-guanylin; Guanylin]. [Source:Uniprot/SWISSPROT;Acc:Q02747]	extracellular region	cellular component	
1.1611	down	Guanylin precursor (Guanylate cyclase activator 2A) (Guanylate cyclase-activating protein 1) (Gap-I) [Contains: HMW-guanylin; Guanylin]. [Source:Uniprot/SWISSPROT;Acc:Q02747]	guanylate cyclase activator activity	molecular function	
1.1611	down	Guanylin precursor (Guanylate cyclase activator 2A) (Guanylate cyclase-activating protein 1) (Gap-I) [Contains: HMW-guanylin; Guanylin]. [Source:Uniprot/SWISSPROT;Acc:Q02747]	hormone activity	molecular function	
1.1611	down	Guanylin precursor (Guanylate cyclase activator 2A) (Guanylate cyclase-activating protein 1) (Gap-I) [Contains: HMW-guanylin; Guanylin]. [Source:Uniprot/SWISSPROT;Acc:Q02747]	signal transduction	biological process	
1.16158	up	transient receptor potential cation channel, subfamily C, member 2 (TRPC2) on chromosome 11 [Source:RefSeq_dna;Acc:NR_002720]	calcium channel activity	molecular function	
1.16158	up	transient receptor potential cation channel, subfamily C, member 2 (TRPC2) on chromosome 11 [Source:RefSeq_dna;Acc:NR_002720]	calcium ion transport	biological process	
1.16158	up	transient receptor potential cation channel, subfamily C, member 2 (TRPC2) on chromosome 11 [Source:RefSeq_dna;Acc:NR_002720]	ion channel activity	molecular function	
1.16158	up	transient receptor potential cation channel, subfamily C, member 2 (TRPC2) on chromosome 11 [Source:RefSeq_dna;Acc:NR_002720]	ion transport	biological process	
1.16158	up	transient receptor potential cation channel, subfamily C, member 2 (TRPC2) on chromosome 11 [Source:RefSeq_dna;Acc:NR_002720]	membrane	cellular component	
1.16173	up	oligonucleotide/oligosaccharide-binding fold containing 2B [Source:RefSeq_peptide;Acc:NP_076973]	nucleic acid binding	molecular function	
1.16363	up	Sperm acrosome membrane-associated protein 1 precursor (Sperm acrosomal membrane-associated protein 32). [Source:Uniprot/SWISSPROT;Acc:Q9HBV2]	integral to membrane	cellular component	
1.16363	up	Sperm acrosome membrane-associated protein 1 precursor (Sperm acrosomal membrane-associated protein 32). [Source:Uniprot/SWISSPROT;Acc:Q9HBV2]	membrane	cellular component	
1.16393	up	olfactory receptor, family 5, subfamily K, member 4 [Source:RefSeq_peptide;Acc:NP_001005517]	G-protein coupled receptor protein signaling pathway	biological process	
1.16393	up	olfactory receptor, family 5, subfamily K, member 4 [Source:RefSeq_peptide;Acc:NP_001005517]	integral to membrane	cellular component	
1.16393	up	olfactory receptor, family 5, subfamily K, member 4 [Source:RefSeq_peptide;Acc:NP_001005517]	olfactory receptor activity	molecular function	
1.16393	up	olfactory receptor, family 5, subfamily K, member 4 [Source:RefSeq_peptide;Acc:NP_001005517]	rhodopsin-like receptor activity	molecular function	
1.16499	up	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3). [Source:Uniprot/SWISSPROT;Acc:Q9P0K1]	cell adhesion	biological process	

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells. 
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component. 
- The Gene Ontology terms as linked to the specific gene.
- http://analysis.yellowcouch.org/