MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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description	Ratio	Regulation	Class	Gene Ontology	Gene	Accession	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 193 to 242 of 2667 in total

description	Ratio	Regulation	Class	Gene Ontology
ATP-binding cassette sub-family A member 3 (ATP-binding cassette transporter 3) (ATP-binding cassette 3) (ABC-C transporter). [Uniprot/SWISSPROT;Acc:Q99758]	1.22502	up	molecular function	nucleotide binding
				transporter activity
ATP-binding domain 1 family member B. [Uniprot/SWISSPROT;Acc:Q9H9Y4]	3.06659	down		ATP binding
				nucleotide binding
ATPase family AAA domain-containing protein 2B. [Uniprot/SWISSPROT;Acc:Q9ULI0]	1.39878	up		ATP binding
				nucleoside-triphosphatase activity
				nucleotide binding
Autophagy-related protein 10 (APG10-like). [Uniprot/SWISSPROT;Acc:Q9H0Y0]	1.28319		biological process	autophagy
				positive regulation of protein modification
				protein amino acid lipidation
				protein transport
				ubiquitin cycle
			cellular component	cytoplasm
				intracellular
			molecular function	protein binding
Bardet-Biedl syndrome 5 protein. [Uniprot/SWISSPROT;Acc:Q8N3I7]	1.34491		biological process	response to stimulus
				visual perception
			cellular component	cellular_component
				cilium
				intracellular
			molecular function	molecular_function
Bcl-2-interacting killer (Apoptosis inducer NBK) (BP4) (BIP1). [Uniprot/SWISSPROT;Acc:Q13323]	1.21871	down	biological process	apoptotic program
				induction of apoptosis
				regulation of apoptosis
			cellular component	integral to membrane
				membrane
				mitochondrial envelope
			molecular function	protein binding
BET1 homolog (Golgi vesicular membrane-trafficking protein p18) (hBET1). [Uniprot/SWISSPROT;Acc:O15155]	2.48474	up	biological process	ER to Golgi vesicle-mediated transport
				protein transport
			cellular component	endoplasmic reticulum
				Golgi apparatus
				Golgi membrane
				integral to membrane
				membrane
			molecular function	protein binding
Beta-defensin 2 precursor (BD-2) (hBD-2) (Defensin, beta 2) (Skin- antimicrobial peptide 1) (SAP1). [Uniprot/SWISSPROT;Acc:O15263]	1.51342	down	biological process	chemotaxis
				defense response
				defense response to bacterium
				G-protein coupled receptor protein signaling pathway
				immune response
			cellular component	extracellular region
Beta-mannosidase precursor (EC 3.2.1.25) (Lysosomal beta A mannosidase) (Mannanase) (Mannase). [Uniprot/SWISSPROT;Acc:O00462]	1.33329	up	biological process	carbohydrate metabolic process
				glycoprotein catabolic process
				metabolic process
				protein modification process
			cellular component	lysosome
			molecular function	beta-mannosidase activity
				cation binding
				hydrolase activity, hydrolyzing O-glycosyl compounds

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.