MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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description	Ratio	Gene	Gene Ontology	Regulation	Class	Accession	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 151 to 200 of 2667 in total

description	Ratio	Gene Ontology	Regulation	Class
Arylamine N-acetyltransferase 1 (EC 2.3.1.5) (Arylamide acetylase 1) (Monomorphic arylamine N-acetyltransferase) (MNAT) (N- acetyltransferase type 1) (NAT-1). [Uniprot/SWISSPROT;Acc:P18440]	3.00923	cytoplasm	down	cellular component
		metabolic process		biological process
		transferase activity		molecular function
Arylamine N-acetyltransferase 2 (EC 2.3.1.5) (Arylamide acetylase 2) (Polymorphic arylamine N-acetyltransferase) (PNAT) (N- acetyltransferase type 2) (NAT-2). [Uniprot/SWISSPROT;Acc:P11245]	4.69231	acetyltransferase activity
		arylamine N-acetyltransferase activity
		cytoplasm		cellular component
		metabolic process		biological process
		transferase activity		molecular function
AT-hook-containing transcription factor 1 (Embryonic large molecule derived from yolk sac). [Uniprot/SWISSPROT;Acc:Q8WYP5]	3.83977	cytoplasm		cellular component
		DNA binding		molecular function
		multicellular organismal development		biological process
		nuclear matrix		cellular component
		nucleus
		regulation of transcription		biological process
		transcription
		transcription factor activity		molecular function
Ataxin-7 (Spinocerebellar ataxia type 7 protein). [Uniprot/SWISSPROT;Acc:O15265]	2.29381	cell death	up	biological process
		chromatin binding		molecular function
		cytoplasm		cellular component
		intracellular
		nuclear organization and biogenesis		biological process
		nucleus		cellular component
		protein binding		molecular function
		visual perception		biological process
		zinc ion binding		molecular function
Atlastin-2 (ADP-ribosylation factor-like protein 6-interacting protein 2). [Uniprot/SWISSPROT;Acc:Q8NHH9]	1.24964	GTP binding	down
		GTPase activity
		immune response		biological process
		integral to membrane		cellular component
		membrane
		nucleotide binding		molecular function
		protein binding
ATP-binding cassette sub-family A member 3 (ATP-binding cassette transporter 3) (ATP-binding cassette 3) (ABC-C transporter). [Uniprot/SWISSPROT;Acc:Q99758]	1.22502	ATP binding	up
		ATPase activity
		ATPase activity, coupled to transmembrane movement of substances
		integral to membrane		cellular component
		lamellar body
		membrane fraction
		nucleoside-triphosphatase activity		molecular function
		nucleotide binding
		plasma membrane		cellular component
		response to drug		biological process
		transport
		transporter activity		molecular function
ATP-binding domain 1 family member B. [Uniprot/SWISSPROT;Acc:Q9H9Y4]	3.06659	ATP binding	down
		nucleotide binding
ATPase family AAA domain-containing protein 2B. [Uniprot/SWISSPROT;Acc:Q9ULI0]	1.39878	ATP binding	up
		nucleoside-triphosphatase activity
		nucleotide binding
Autophagy-related protein 10 (APG10-like). [Uniprot/SWISSPROT;Acc:Q9H0Y0]	1.28319	autophagy		biological process

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.