Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Ratio Regulation description Class Gene Ontology Gene Accession Minimum Ratio Maximum Ratio

Results: HTML CSV LaTeX

Showing element 1 to 12 of 12 in total

Class	cellular component
Gene Ontology	plasma membrane

Ratio	Regulation	description	
1.11083	down	Sodium- and chloride-dependent transporter XTRP3 (Solute carrier family 6 member 20) (Neurotransmitter transporter rB21A homolog). [Source:Uniprot/SWISSPROT;Acc:Q9NP91]	
1.20102	up	Metalloreductase STEAP3 (EC 1.16.1.-) (Six-transmembrane epithelial antigen of prostate 3) (Tumor suppressor-activated pathway protein 6) (hTSAP6) (pHyde) (hpHyde) (Dudulin-2). [Source:Uniprot/SWISSPROT;Acc:Q658P3]	
1.21657	up	Septin-5 (Peanut-like protein 1) (Cell division control-related protein 1) (CDCrel-1). [Source:Uniprot/SWISSPROT;Acc:Q99719]	
1.22502	up	ATP-binding cassette sub-family A member 3 (ATP-binding cassette transporter 3) (ATP-binding cassette 3) (ABC-C transporter). [Source:Uniprot/SWISSPROT;Acc:Q99758]	
1.25147	up	T-lymphocyte activation antigen CD86 precursor (Activation B7-2 antigen) (CTLA-4 counter-receptor B7.2) (B70) (FUN-1) (BU63). [Source:Uniprot/SWISSPROT;Acc:P42081]	
1.4628	up	Poliovirus receptor-related protein 3 precursor (Nectin-3) (CD113 antigen) (CDw113). [Source:Uniprot/SWISSPROT;Acc:Q9NQS3]	
1.60668	up	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC [Source:Uniprot/SWISSPROT;Acc:Q9HBA0]	
1.61987	up	Proteinase-activated receptor 1 precursor (PAR-1) (Thrombin receptor) (Coagulation factor II receptor). [Source:Uniprot/SWISSPROT;Acc:P25116]	
1.63639	up	Cysteine-rich hydrophobic domain 2 protein (BrX-like translocated in leukemia). [Source:Uniprot/SWISSPROT;Acc:Q9UKJ5]	
1.76994	down	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha). [Source:Uniprot/SWISSPROT;Acc:O43184]	
2.44552	down	Guanine nucleotide-binding protein alpha-14 subunit (G-protein alpha subunit 14). [Source:Uniprot/SWISSPROT;Acc:O95837]	
4.62042	down	Leukocyte antigen CD37 (Tetraspanin-26) (Tspan-26). [Source:Uniprot/SWISSPROT;Acc:P11049]	

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells. 
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component. 
- The Gene Ontology terms as linked to the specific gene.

- http://analysis.yellowcouch.org/