Scientific

MK5 Microarray Data


Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes


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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Ratio Regulation Class description Gene Ontology Gene Accession Minimum Ratio Maximum Ratio
Results: HTML CSV LaTeX Showing element 1 to 15 of 15 in total
Class: biological process
Gene Ontology: multicellular organismal development
\def\wcA{0.25\textwidth} \def\wcB{0.25\textwidth} \def\wcC{0.25\textwidth} \begin{longtable}{|c|c|c|} \hline \parbox{\wcA}{\vspace{3pt}\noindent Ratio\vspace{3pt}}&\parbox{\wcB}{\vspace{3pt}\noindent Regulation\vspace{3pt}}&\parbox{\wcC}{\vspace{3pt}\noindent description\vspace{3pt}}\\ \hline \hline \parbox{\wcA}{\vspace{3pt}\noindent 1.10831\vspace{3pt}}&\multirow{4}{*}{\parbox{\wcB}{\vspace{3pt}\noindent up\vspace{3pt}}}&\parbox{\wcC}{\vspace{3pt}\noindent Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein). \vspace{3pt}}\\\cline{1-1}\cline{3-3} \parbox{\wcA}{\vspace{3pt}\noindent 1.16921\vspace{3pt}}&&\parbox{\wcC}{\vspace{3pt}\noindent Transcription cofactor HES-6 (Hairy and enhancer of split 6) (C- HAIRY1). \vspace{3pt}}\\\cline{1-1}\cline{3-3} \parbox{\wcA}{\vspace{3pt}\noindent 1.19207\vspace{3pt}}&&\parbox{\wcC}{\vspace{3pt}\noindent Nuclear RNA export factor 2 (TAP-like protein 2) (TAPL-2). \vspace{3pt}}\\\cline{1-1}\cline{3-3} \parbox{\wcA}{\vspace{3pt}\noindent 1.19545\vspace{3pt}}&&\parbox{\wcC}{\vspace{3pt}\noindent Deoxyribonuclease-2-alpha precursor (EC 3.1.22.1) (Deoxyribonuclease II alpha) (DNase II alpha) (Acid DNase) (Lysosomal DNase II) (R31240\_2). \vspace{3pt}}\\\hline \parbox{\wcA}{\vspace{3pt}\noindent 1.27461\vspace{3pt}}&\multirow{3}{*}{\parbox{\wcB}{\vspace{3pt}\noindent down\vspace{3pt}}}&\parbox{\wcC}{\vspace{3pt}\noindent Homeobox protein Hox-D3 (Hox-4A). \vspace{3pt}}\\\cline{1-1}\cline{3-3} \parbox{\wcA}{\vspace{3pt}\noindent 1.27696\vspace{3pt}}&&\parbox{\wcC}{\vspace{3pt}\noindent Speedy protein A (Speedy-1) (Spy1) (Rapid inducer of G2/M progression in oocytes A) (RINGO A) (hSpy/Ringo A). \vspace{3pt}}\\\cline{1-1}\cline{3-3} \parbox{\wcA}{\vspace{3pt}\noindent 1.28356\vspace{3pt}}&&\parbox{\wcC}{\vspace{3pt}\noindent T-box transcription factor TBX2 (T-box protein 2). \vspace{3pt}}\\\hline \parbox{\wcA}{\vspace{3pt}\noindent 1.30407\vspace{3pt}}&\multirow{5}{*}{\parbox{\wcB}{\vspace{3pt}\noindent up\vspace{3pt}}}&\parbox{\wcC}{\vspace{3pt}\noindent Homeobox protein Nkx-2.8 (Homeobox protein NK-2 homolog H). \vspace{3pt}}\\\cline{1-1}\cline{3-3} \parbox{\wcA}{\vspace{3pt}\noindent 1.33465\vspace{3pt}}&&\parbox{\wcC}{\vspace{3pt}\noindent T-box transcription factor TBX5 (T-box protein 5). \vspace{3pt}}\\\cline{1-1}\cline{3-3} \parbox{\wcA}{\vspace{3pt}\noindent 1.36997\vspace{3pt}}&&\parbox{\wcC}{\vspace{3pt}\noindent Rho GTPase-activating protein 24 (Rho-type GTPase-activating protein 24) (Filamin-A-associated RhoGAP) (FilGAP) (p73RhoGAP) (RhoGAP of 73 kDa) (RAC1- and CDC42-specific GTPase-activating protein of 72 kDa) (RC-GAP72) (Sarcoma antigen NY-SAR-88). \vspace{3pt}}\\\cline{1-1}\cline{3-3} \parbox{\wcA}{\vspace{3pt}\noindent 1.45624\vspace{3pt}}&&\parbox{\wcC}{\vspace{3pt}\noindent Transcription factor NF-E2 45 kDa subunit (Nuclear factor, erythroid- derived 2 45 kDa subunit) (p45 NF-E2) (Leucine zipper protein NF-E2). \vspace{3pt}}\\\cline{1-1}\cline{3-3} \parbox{\wcA}{\vspace{3pt}\noindent 1.61987\vspace{3pt}}&&\parbox{\wcC}{\vspace{3pt}\noindent Proteinase-activated receptor 1 precursor (PAR-1) (Thrombin receptor) (Coagulation factor II receptor). \vspace{3pt}}\\\hline \parbox{\wcA}{\vspace{3pt}\noindent 2.58329\vspace{3pt}}&\parbox{\wcB}{\vspace{3pt}\noindent down\vspace{3pt}}&\parbox{\wcC}{\vspace{3pt}\noindent Myelin transcription factor 1-like protein (MyT1L protein) (MyT1-L). \vspace{3pt}}\\\hline \parbox{\wcA}{\vspace{3pt}\noindent 3.70292\vspace{3pt}}&\parbox{\wcB}{\vspace{3pt}\noindent up\vspace{3pt}}&\parbox{\wcC}{\vspace{3pt}\noindent Homeobox protein SIX4 (Sine oculis homeobox homolog 4). \vspace{3pt}}\\\hline \parbox{\wcA}{\vspace{3pt}\noindent 3.83977\vspace{3pt}}&\parbox{\wcB}{\vspace{3pt}\noindent down\vspace{3pt}}&\parbox{\wcC}{\vspace{3pt}\noindent AT-hook-containing transcription factor 1 (Embryonic large molecule derived from yolk sac). \vspace{3pt}}\\\hline nd{longtable}
Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.

- http://analysis.yellowcouch.org/