Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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Regulation Ratio description Class Gene Ontology Gene Accession Minimum Ratio Maximum Ratio

Results: HTML CSV LaTeX

Showing element 2619 to 2667 of 2667 in total

Regulation	up

Ratio	description	Class	Gene Ontology	
5.19755	Adiponectin receptor protein 1 (Progestin and adipoQ receptor family member I). [Source:Uniprot/SWISSPROT;Acc:Q96A54]	cellular component	integral to membrane	
5.19755	Adiponectin receptor protein 1 (Progestin and adipoQ receptor family member I). [Source:Uniprot/SWISSPROT;Acc:Q96A54]	cellular component	membrane	
5.19755	Adiponectin receptor protein 1 (Progestin and adipoQ receptor family member I). [Source:Uniprot/SWISSPROT;Acc:Q96A54]	molecular function	hormone binding	
5.19755	Adiponectin receptor protein 1 (Progestin and adipoQ receptor family member I). [Source:Uniprot/SWISSPROT;Acc:Q96A54]	molecular function	identical protein binding	
5.19755	Adiponectin receptor protein 1 (Progestin and adipoQ receptor family member I). [Source:Uniprot/SWISSPROT;Acc:Q96A54]	molecular function	protein heterodimerization activity	
5.19755	Adiponectin receptor protein 1 (Progestin and adipoQ receptor family member I). [Source:Uniprot/SWISSPROT;Acc:Q96A54]	molecular function	receptor activity	
5.31521	Rho-related BTB domain-containing protein 1. [Source:Uniprot/SWISSPROT;Acc:O94844]	biological process	protein transport	
5.31521	Rho-related BTB domain-containing protein 1. [Source:Uniprot/SWISSPROT;Acc:O94844]	biological process	small GTPase mediated signal transduction	
5.31521	Rho-related BTB domain-containing protein 1. [Source:Uniprot/SWISSPROT;Acc:O94844]	cellular component	intracellular	
5.31521	Rho-related BTB domain-containing protein 1. [Source:Uniprot/SWISSPROT;Acc:O94844]	molecular function	GTP binding	
5.31521	Rho-related BTB domain-containing protein 1. [Source:Uniprot/SWISSPROT;Acc:O94844]	molecular function	nucleotide binding	
5.31521	Rho-related BTB domain-containing protein 1. [Source:Uniprot/SWISSPROT;Acc:O94844]	molecular function	protein binding	
5.53059	rab and DnaJ domain containing [Source:RefSeq_peptide;Acc:NP_057628]	biological process	intracellular protein transport	
5.53059	rab and DnaJ domain containing [Source:RefSeq_peptide;Acc:NP_057628]	biological process	nucleocytoplasmic transport	
5.53059	rab and DnaJ domain containing [Source:RefSeq_peptide;Acc:NP_057628]	biological process	protein transport	
5.53059	rab and DnaJ domain containing [Source:RefSeq_peptide;Acc:NP_057628]	biological process	signal transduction	
5.53059	rab and DnaJ domain containing [Source:RefSeq_peptide;Acc:NP_057628]	biological process	small GTPase mediated signal transduction	
5.53059	rab and DnaJ domain containing [Source:RefSeq_peptide;Acc:NP_057628]	cellular component	intracellular	
5.53059	rab and DnaJ domain containing [Source:RefSeq_peptide;Acc:NP_057628]	molecular function	GTP binding	
5.53059	rab and DnaJ domain containing [Source:RefSeq_peptide;Acc:NP_057628]	molecular function	GTPase activity	
5.53059	rab and DnaJ domain containing [Source:RefSeq_peptide;Acc:NP_057628]	molecular function	heat shock protein binding	
5.53059	rab and DnaJ domain containing [Source:RefSeq_peptide;Acc:NP_057628]	molecular function	nucleotide binding	
5.53059	rab and DnaJ domain containing [Source:RefSeq_peptide;Acc:NP_057628]	molecular function	protein binding	
5.81102	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (PDZ-LIM protein). [Source:Uniprot/SWISSPROT;Acc:Q96JY6]	cellular component	cell surface	
5.81102	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (PDZ-LIM protein). [Source:Uniprot/SWISSPROT;Acc:Q96JY6]	cellular component	cytoplasm	
5.81102	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (PDZ-LIM protein). [Source:Uniprot/SWISSPROT;Acc:Q96JY6]	cellular component	cytoskeleton	
5.81102	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (PDZ-LIM protein). [Source:Uniprot/SWISSPROT;Acc:Q96JY6]	cellular component	nucleus	
5.81102	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (PDZ-LIM protein). [Source:Uniprot/SWISSPROT;Acc:Q96JY6]	molecular function	metal ion binding	
5.81102	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (PDZ-LIM protein). [Source:Uniprot/SWISSPROT;Acc:Q96JY6]	molecular function	protein binding	
5.81102	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (PDZ-LIM protein). [Source:Uniprot/SWISSPROT;Acc:Q96JY6]	molecular function	zinc ion binding	
6.50865	Serine/threonine-protein kinase Nek10 (EC 2.7.11.1) (NimA-related protein kinase 10). [Source:Uniprot/SWISSPROT;Acc:Q6ZWH5]	biological process	protein amino acid phosphorylation	
6.50865	Serine/threonine-protein kinase Nek10 (EC 2.7.11.1) (NimA-related protein kinase 10). [Source:Uniprot/SWISSPROT;Acc:Q6ZWH5]	molecular function	ATP binding	
6.50865	Serine/threonine-protein kinase Nek10 (EC 2.7.11.1) (NimA-related protein kinase 10). [Source:Uniprot/SWISSPROT;Acc:Q6ZWH5]	molecular function	magnesium ion binding	
6.50865	Serine/threonine-protein kinase Nek10 (EC 2.7.11.1) (NimA-related protein kinase 10). [Source:Uniprot/SWISSPROT;Acc:Q6ZWH5]	molecular function	nucleotide binding	
6.50865	Serine/threonine-protein kinase Nek10 (EC 2.7.11.1) (NimA-related protein kinase 10). [Source:Uniprot/SWISSPROT;Acc:Q6ZWH5]	molecular function	protein kinase activity	
6.50865	Serine/threonine-protein kinase Nek10 (EC 2.7.11.1) (NimA-related protein kinase 10). [Source:Uniprot/SWISSPROT;Acc:Q6ZWH5]	molecular function	protein serine/threonine kinase activity	
6.50865	Serine/threonine-protein kinase Nek10 (EC 2.7.11.1) (NimA-related protein kinase 10). [Source:Uniprot/SWISSPROT;Acc:Q6ZWH5]	molecular function	protein-tyrosine kinase activity	
6.50865	Serine/threonine-protein kinase Nek10 (EC 2.7.11.1) (NimA-related protein kinase 10). [Source:Uniprot/SWISSPROT;Acc:Q6ZWH5]	molecular function	transferase activity	
7.27043	Short palate, lung and nasal epithelium carcinoma-associated protein 3 precursor. [Source:Uniprot/SWISSPROT;Acc:Q9BQP9]	molecular function	lipid binding	
8.21788	Ubiquitin-activating enzyme E1 domain-containing protein 1 (UFM1- activating enzyme) (Ubiquitin-activating enzyme 5) (ThiFP1). [Source:Uniprot/SWISSPROT;Acc:Q9GZZ9]	biological process	defense response	
8.21788	Ubiquitin-activating enzyme E1 domain-containing protein 1 (UFM1- activating enzyme) (Ubiquitin-activating enzyme 5) (ThiFP1). [Source:Uniprot/SWISSPROT;Acc:Q9GZZ9]	biological process	humoral immune response	
8.21788	Ubiquitin-activating enzyme E1 domain-containing protein 1 (UFM1- activating enzyme) (Ubiquitin-activating enzyme 5) (ThiFP1). [Source:Uniprot/SWISSPROT;Acc:Q9GZZ9]	biological process	ubiquitin cycle	
8.21788	Ubiquitin-activating enzyme E1 domain-containing protein 1 (UFM1- activating enzyme) (Ubiquitin-activating enzyme 5) (ThiFP1). [Source:Uniprot/SWISSPROT;Acc:Q9GZZ9]	cellular component	cytoplasm	
8.21788	Ubiquitin-activating enzyme E1 domain-containing protein 1 (UFM1- activating enzyme) (Ubiquitin-activating enzyme 5) (ThiFP1). [Source:Uniprot/SWISSPROT;Acc:Q9GZZ9]	cellular component	nucleus	
8.21788	Ubiquitin-activating enzyme E1 domain-containing protein 1 (UFM1- activating enzyme) (Ubiquitin-activating enzyme 5) (ThiFP1). [Source:Uniprot/SWISSPROT;Acc:Q9GZZ9]	molecular function	catalytic activity	
8.21788	Ubiquitin-activating enzyme E1 domain-containing protein 1 (UFM1- activating enzyme) (Ubiquitin-activating enzyme 5) (ThiFP1). [Source:Uniprot/SWISSPROT;Acc:Q9GZZ9]	molecular function	cofactor binding	
8.21788	Ubiquitin-activating enzyme E1 domain-containing protein 1 (UFM1- activating enzyme) (Ubiquitin-activating enzyme 5) (ThiFP1). [Source:Uniprot/SWISSPROT;Acc:Q9GZZ9]	molecular function	DNA binding	
8.21788	Ubiquitin-activating enzyme E1 domain-containing protein 1 (UFM1- activating enzyme) (Ubiquitin-activating enzyme 5) (ThiFP1). [Source:Uniprot/SWISSPROT;Acc:Q9GZZ9]	molecular function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	
8.21788	Ubiquitin-activating enzyme E1 domain-containing protein 1 (UFM1- activating enzyme) (Ubiquitin-activating enzyme 5) (ThiFP1). [Source:Uniprot/SWISSPROT;Acc:Q9GZZ9]	molecular function	translation regulator activity	

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells. 
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component. 
- The Gene Ontology terms as linked to the specific gene.

- http://analysis.yellowcouch.org/