MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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Regulation	description	Ratio	Class	Gene Ontology	Gene	Minimum Ratio	Accession	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 593 to 642 of 2667 in total

Regulation  : down

description	Ratio	Class	Gene Ontology
Melanoma-associated antigen C2 (MAGE-C2 antigen) (MAGE-E1 antigen) (Hepatocellular carcinoma-associated antigen 587) (Cancer-testis antigen 10) (CT10). [Uniprot/SWISSPROT;Acc:Q9UBF1]	1.29952	cellular component	nucleus
Myelin transcription factor 1-like protein (MyT1L protein) (MyT1-L). [Uniprot/SWISSPROT;Acc:Q9UL68]	2.58329	biological process	cell differentiation
			multicellular organismal development
			nervous system development
			regulation of transcription, DNA-dependent
			transcription
		cellular component	nucleus
		molecular function	calcium ion binding
			metal ion binding
			transcription factor activity
			zinc ion binding
Myosin-15 (Myosin heavy chain 15). [Uniprot/SWISSPROT;Acc:Q9Y2K3]	1.24114	biological process	signal transduction
			striated muscle contraction
		cellular component	intracellular
			myosin complex
			striated muscle thick filament
		molecular function	actin binding
			ATP binding
			calmodulin binding
			motor activity
			nucleotide binding
Myosin-If (Myosin-Ie). [Uniprot/SWISSPROT;Acc:O00160]	1.23668	biological process	biological_process
		cellular component	myosin complex
			unconventional myosin complex
		molecular function	actin binding
			ATP binding
			calmodulin binding
			motor activity
			nucleoside-triphosphatase activity
			nucleotide binding
Neurosecretory protein VGF precursor. [Uniprot/SWISSPROT;Acc:O15240]	1.20481	biological process	biological_process
			generation of precursor metabolites and energy
			ovarian follicle development
			sexual reproduction
		cellular component	cellular_component
			cytoplasmic vesicle
		molecular function	growth factor activity
			neuropeptide hormone activity
Ninein-like protein. [Uniprot/SWISSPROT;Acc:Q9Y2I6]	3.15011	cellular component	cytoplasm
			microtubule
		molecular function	calcium ion binding
Nuclear factor of activated T-cells, cytoplasmic 3 (NF-ATc3) (NFATc3) (T cell transcription factor NFAT4) (NF-AT4) (NFATx). [Uniprot/SWISSPROT;Acc:Q12968]	5.32612	biological process	cellular respiration
			heart development
			inflammatory response
			regulation of transcription
			regulation of transcription from RNA polymerase II promoter
			regulation of transcription, DNA-dependent
		cellular component	cytoplasm
			nucleus
		molecular function	protein binding

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.