MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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description	Ratio	Regulation	Gene Ontology	Class	Gene	Accession	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 551 to 600 of 2667 in total

description	Ratio	Regulation	Gene Ontology	Class
CLIP-associating protein 2 (Cytoplasmic linker-associated protein 2) (hOrbit2). [Uniprot/SWISSPROT;Acc:O75122]	1.29151	up	cytoskeleton	cellular component
			establishment and/or maintenance of cell polarity	biological process
			galactoside 2-alpha-L-fucosyltransferase activity	molecular function
			Golgi apparatus	cellular component
			kinetochore microtubule
			microtubule binding	molecular function
			microtubule plus-end binding
			mitosis	biological process
			negative regulation of microtubule depolymerization
			protein binding	molecular function
			regulation of microtubule polymerization or depolymerization	biological process
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase (EC 2.4.99.-) (Beta-galactoside alpha-2,3-sialyltransferase) (Alpha 2,3-sialyltransferase IV) (Alpha 2,3-ST) (Gal-NAc6S) (STZ) (SIAT4-C) (ST3Gal III) (SAT-3) (ST-4). [Uniprot/SWISSPROT;Acc:Q11206]	1.69658	down	beta-galactoside alpha-2,3-sialyltransferase activity	molecular function
			Golgi apparatus	cellular component
			integral to Golgi membrane
			integral to membrane
			membrane
			protein amino acid glycosylation	biological process
			sialyltransferase activity	molecular function
			transferase activity, transferring glycosyl groups
Coiled-coil and C2 domain-containing protein 1B. [Uniprot/SWISSPROT;Acc:Q5T0F9]	1.29238	up	FAD binding
			oxidoreductase activity
coiled-coil domain containing 90A [RefSeq_peptide;Acc:NP_001026883]	1.83601		G-protein coupled receptor protein signaling pathway	biological process
			integral to membrane	cellular component
			membrane
			mitochondrion
Coiled-coil domain-containing protein 108. [Uniprot/SWISSPROT;Acc:Q6ZU64]	1.72628	down	DNA repair	biological process
			integral to membrane	cellular component
			membrane
			methylated-DNA-[protein]-cysteine S-methyltransferase activity	molecular function
			structural molecule activity
Coiled-coil domain-containing protein 83. [Uniprot/SWISSPROT;Acc:Q8IWF9]	2.37788	up
			viral capsid	cellular component
collagen, type XXVII, alpha 1 [RefSeq_peptide;Acc:NP_116277]	1.40749		cell adhesion	biological process
			collagen	cellular component
			cytoplasm
			dopamine receptor activity	molecular function
			extracellular matrix structural constituent
			G-protein coupled receptor protein signaling pathway	biological process
			integral to membrane	cellular component
			phosphate transport	biological process
			structural constituent of cell wall	molecular function
			structural molecule activity
Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein). [Uniprot/SWISSPROT;Acc:Q9P232]	3.99682	down	ATP binding
			cell adhesion	biological process
			GPI anchor binding	molecular function
			interleukin-1 receptor activity
			membrane	cellular component
			protein amino acid phosphorylation	biological process
			protein binding	molecular function
			vascular endothelial growth factor receptor activity

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.