MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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description	Ratio	Regulation	Class	Gene Ontology	Gene	Accession	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 551 to 600 of 2667 in total

description	Ratio	Regulation	Class	Gene Ontology
CLIP-associating protein 2 (Cytoplasmic linker-associated protein 2) (hOrbit2). [Uniprot/SWISSPROT;Acc:O75122]	1.29151	up	biological process	regulation of microtubule polymerization or depolymerization
			cellular component	cytoplasm
				cytoplasmic microtubule
				cytoskeleton
				Golgi apparatus
				kinetochore microtubule
			molecular function	binding
				galactoside 2-alpha-L-fucosyltransferase activity
				microtubule binding
				microtubule plus-end binding
				protein binding
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase (EC 2.4.99.-) (Beta-galactoside alpha-2,3-sialyltransferase) (Alpha 2,3-sialyltransferase IV) (Alpha 2,3-ST) (Gal-NAc6S) (STZ) (SIAT4-C) (ST3Gal III) (SAT-3) (ST-4). [Uniprot/SWISSPROT;Acc:Q11206]	1.69658	down	biological process	protein amino acid glycosylation
			cellular component	Golgi apparatus
				integral to Golgi membrane
				integral to membrane
				membrane
			molecular function	beta-galactoside alpha-2,3-sialyltransferase activity
				sialyltransferase activity
				transferase activity, transferring glycosyl groups
Coiled-coil and C2 domain-containing protein 1B. [Uniprot/SWISSPROT;Acc:Q5T0F9]	1.29238	up		FAD binding
				oxidoreductase activity
coiled-coil domain containing 90A [RefSeq_peptide;Acc:NP_001026883]	1.83601		biological process	G-protein coupled receptor protein signaling pathway
			cellular component	integral to membrane
				membrane
				mitochondrion
Coiled-coil domain-containing protein 108. [Uniprot/SWISSPROT;Acc:Q6ZU64]	1.72628	down	biological process	DNA repair
			cellular component	integral to membrane
				membrane
			molecular function	methylated-DNA-[protein]-cysteine S-methyltransferase activity
				structural molecule activity
Coiled-coil domain-containing protein 83. [Uniprot/SWISSPROT;Acc:Q8IWF9]	2.37788	up	cellular component	viral capsid
			molecular function	structural molecule activity
collagen, type XXVII, alpha 1 [RefSeq_peptide;Acc:NP_116277]	1.40749		biological process	cell adhesion
				G-protein coupled receptor protein signaling pathway
				phosphate transport
			cellular component	collagen
				cytoplasm
				integral to membrane
			molecular function	dopamine receptor activity
				extracellular matrix structural constituent
				structural constituent of cell wall
				structural molecule activity
Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein). [Uniprot/SWISSPROT;Acc:Q9P232]	3.99682	down	biological process	cell adhesion
				protein amino acid phosphorylation
			cellular component	membrane
			molecular function	ATP binding
				GPI anchor binding
				interleukin-1 receptor activity
				protein binding
				vascular endothelial growth factor receptor activity

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.