MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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description	Ratio	Regulation	Gene Ontology	Class	Gene	Accession	Minimum Ratio	Maximum Ratio

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Showing element 501 to 550 of 2667 in total

Regulation  : up

description	Ratio	Gene Ontology	Class
Chromodomain-helicase-DNA-binding protein 7 (EC 3.6.1.-) (ATP- dependent helicase CHD7) (CHD-7). [Uniprot/SWISSPROT;Acc:Q9P2D1]	1.25808	female genitalia development	biological process
		heart morphogenesis
		helicase activity	molecular function
		hydrolase activity
		in utero embryonic development	biological process
		inner ear morphogenesis
		locomotory behavior
		nose development
		nucleic acid binding	molecular function
		nucleotide binding
		nucleus	cellular component
		palate development	biological process
		positive regulation of body size
		regulation of transcription, DNA-dependent
		sensory perception of sound
		transcription
Cisplatin resistance-associated overexpressed protein (cAMP regulatory element-associated protein 1) (CRE-associated protein 1) (CREAP-1) (Luc7A) (Okadaic acid-inducible phosphoprotein OA48-18). [Uniprot/SWISSPROT;Acc:O95232]	2.91954	apoptosis
		DNA binding	molecular function
		nucleus	cellular component
		protein binding	molecular function
		response to stress	biological process
		RNA splicing
CKLF-like MARVEL transmembrane domain-containing protein 4 (Chemokine- like factor superfamily member 4). [Uniprot/SWISSPROT;Acc:Q8IZR5]	1.86433	ATP binding	molecular function
		ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
		cation transport	biological process
		chemotaxis
		cytokine activity	molecular function
		extracellular space	cellular component
		integral to membrane
		membrane
Clarin-1 (Usher syndrome type-3 protein). [Uniprot/SWISSPROT;Acc:P58418]	4.05743	integral to membrane
		membrane
		response to stimulus	biological process
		sensory perception of sound
		visual perception
Claudin-11 (Oligodendrocyte-specific protein). [Uniprot/SWISSPROT;Acc:O75508]	1.75026	axon ensheathment
		calcium-independent cell-cell adhesion
		cell adhesion
		cell junction	cellular component
		identical protein binding	molecular function
		integral to membrane	cellular component
		membrane
		spermatogenesis	biological process
		structural molecule activity	molecular function
		tight junction	cellular component
CLIP-associating protein 2 (Cytoplasmic linker-associated protein 2) (hOrbit2). [Uniprot/SWISSPROT;Acc:O75122]	1.29151	binding	molecular function
		cell cycle	biological process
		cell division
		cytoplasm	cellular component
		cytoplasmic microtubule

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.