MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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description	Ratio	Regulation	Gene Ontology	Class	Gene	Accession	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 51 to 100 of 688 in total

Class  : cellular component

description	Ratio	Regulation	Gene Ontology
AT-hook-containing transcription factor 1 (Embryonic large molecule derived from yolk sac). [Uniprot/SWISSPROT;Acc:Q8WYP5]	3.83977	down	nucleus
Ataxin-7 (Spinocerebellar ataxia type 7 protein). [Uniprot/SWISSPROT;Acc:O15265]	2.29381	up	cytoplasm
			intracellular
			nucleus
Atlastin-2 (ADP-ribosylation factor-like protein 6-interacting protein 2). [Uniprot/SWISSPROT;Acc:Q8NHH9]	1.24964	down	integral to membrane
			membrane
ATP-binding cassette sub-family A member 3 (ATP-binding cassette transporter 3) (ATP-binding cassette 3) (ABC-C transporter). [Uniprot/SWISSPROT;Acc:Q99758]	1.22502	up	integral to membrane
			lamellar body
			membrane fraction
			plasma membrane
Autophagy-related protein 10 (APG10-like). [Uniprot/SWISSPROT;Acc:Q9H0Y0]	1.28319		cytoplasm
			intracellular
Bardet-Biedl syndrome 5 protein. [Uniprot/SWISSPROT;Acc:Q8N3I7]	1.34491		cellular_component
			cilium
			intracellular
Bcl-2-interacting killer (Apoptosis inducer NBK) (BP4) (BIP1). [Uniprot/SWISSPROT;Acc:Q13323]	1.21871	down	integral to membrane
			membrane
			mitochondrial envelope
BET1 homolog (Golgi vesicular membrane-trafficking protein p18) (hBET1). [Uniprot/SWISSPROT;Acc:O15155]	2.48474	up	endoplasmic reticulum
			Golgi apparatus
			Golgi membrane
			integral to membrane
			membrane
Beta-defensin 2 precursor (BD-2) (hBD-2) (Defensin, beta 2) (Skin- antimicrobial peptide 1) (SAP1). [Uniprot/SWISSPROT;Acc:O15263]	1.51342	down	extracellular region
Beta-mannosidase precursor (EC 3.2.1.25) (Lysosomal beta A mannosidase) (Mannanase) (Mannase). [Uniprot/SWISSPROT;Acc:O00462]	1.33329	up	lysosome
Bone morphogenetic protein 2 precursor (BMP-2) (BMP-2A). [Uniprot/SWISSPROT;Acc:P12643]	1.49558	down	extracellular region
			extracellular space
BTB/POZ domain-containing protein KCTD8. [Uniprot/SWISSPROT;Acc:Q6ZWB6]	1.73291	up	membrane
			voltage-gated potassium channel complex
Calcium-dependent secretion activator 2 (Calcium-dependent activator protein for secretion 2) (CAPS-2). [Uniprot/SWISSPROT;Acc:Q86UW7]	1.24359	down	cell junction
			cytoplasmic vesicle
			membrane
			synapse
Calcium/calmodulin-dependent protein kinase type 1B (EC 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase). [Uniprot/SWISSPROT;Acc:Q6P2M8]	1.61673	up	cytoplasm
			nucleus
Calcyphosin-2 (Calcyphosine-2). [Uniprot/SWISSPROT;Acc:Q9BXY5]	1.29424	down	flagellin-based flagellum
Calmodulin-like protein 5 (Calmodulin-like skin protein). [Uniprot/SWISSPROT;Acc:Q9NZT1]	1.61347
Calpain-3 (EC 3.4.22.54) (Calpain L3) (Calpain p94) (Calcium-activated neutral proteinase 3) (CANP 3) (Muscle-specific calcium-activated neutral protease 3) (nCL-1). [Uniprot/SWISSPROT;Acc:P20807]	2.87038	up	cytoplasm
			intracellular
			nucleus
Calsenilin (Kv channel-interacting protein 3) (KChIP3) (A-type potassium channel modulatory protein 3) (DRE-antagonist modulator) (DREAM). [Uniprot/SWISSPROT;Acc:Q9Y2W7]	3.27919	down	cytoplasm
			cytosol
			endoplasmic reticulum
			Golgi apparatus
			membrane
			nucleus
Canalicular multispecific organic anion transporter 2 (ATP-binding cassette sub-family C member 3) (Multidrug resistance-associated protein 3) (Multi-specific organic anion transporter-D) (MOAT-D). [Uniprot/SWISSPROT;Acc:O15438]	1.30802		integral to membrane
			integral to plasma membrane
			membrane
			membrane fraction

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.