MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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description	Ratio	Gene Ontology	Regulation	Class	Gene	Accession	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 51 to 100 of 1501 in total

Regulation  : up

description	Ratio	Gene Ontology	Class
Ataxin-7 (Spinocerebellar ataxia type 7 protein). [Uniprot/SWISSPROT;Acc:O15265]	2.29381	chromatin binding	molecular function
		cytoplasm	cellular component
		intracellular
		nuclear organization and biogenesis	biological process
		nucleus	cellular component
		protein binding	molecular function
		visual perception	biological process
		zinc ion binding	molecular function
ATP-binding cassette sub-family A member 3 (ATP-binding cassette transporter 3) (ATP-binding cassette 3) (ABC-C transporter). [Uniprot/SWISSPROT;Acc:Q99758]	1.22502	ATP binding
		ATPase activity
		ATPase activity, coupled to transmembrane movement of substances
		integral to membrane	cellular component
		lamellar body
		membrane fraction
		nucleoside-triphosphatase activity	molecular function
		nucleotide binding
		plasma membrane	cellular component
		response to drug	biological process
		transport
		transporter activity	molecular function
ATPase family AAA domain-containing protein 2B. [Uniprot/SWISSPROT;Acc:Q9ULI0]	1.39878	ATP binding
		nucleoside-triphosphatase activity
		nucleotide binding
Autophagy-related protein 10 (APG10-like). [Uniprot/SWISSPROT;Acc:Q9H0Y0]	1.28319	autophagy	biological process
		cytoplasm	cellular component
		intracellular
		positive regulation of protein modification	biological process
		protein amino acid lipidation
		protein binding	molecular function
		protein transport	biological process
		ubiquitin cycle
Bardet-Biedl syndrome 5 protein. [Uniprot/SWISSPROT;Acc:Q8N3I7]	1.34491	cellular_component	cellular component
		cilium
		intracellular
		molecular_function	molecular function
		response to stimulus	biological process
		visual perception
BET1 homolog (Golgi vesicular membrane-trafficking protein p18) (hBET1). [Uniprot/SWISSPROT;Acc:O15155]	2.48474	endoplasmic reticulum	cellular component
		ER to Golgi vesicle-mediated transport	biological process
		Golgi apparatus	cellular component
		Golgi membrane
		integral to membrane
		membrane
		protein binding	molecular function
		protein transport	biological process
Beta-mannosidase precursor (EC 3.2.1.25) (Lysosomal beta A mannosidase) (Mannanase) (Mannase). [Uniprot/SWISSPROT;Acc:O00462]	1.33329	beta-mannosidase activity	molecular function
		carbohydrate metabolic process	biological process
		cation binding	molecular function
		glycoprotein catabolic process	biological process
		hydrolase activity, hydrolyzing O-glycosyl compounds	molecular function

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.