MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

description	Ratio	Class	Regulation	Accession	Gene	Gene Ontology	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 2569 to 2618 of 2667 in total

description	Ratio	Class	Regulation	Gene Ontology
Wee1-like protein kinase (EC 2.7.10.2) (Wee1A kinase) (WEE1hu). [Uniprot/SWISSPROT;Acc:P30291]	1.48363	molecular function	down	nucleotide binding
				protein binding
				protein kinase activity
				protein serine/threonine kinase activity
				protein-tyrosine kinase activity
				transferase activity
X box-binding protein 1 (XBP-1) (Tax-responsive element-binding protein 5). [Uniprot/SWISSPROT;Acc:P17861]	4.4149	biological process		immune response
				regulation of transcription
				regulation of transcription, DNA-dependent
				transcription
		cellular component		nucleus
		molecular function		DNA binding
				protein dimerization activity
				sequence-specific DNA binding
				transcription factor activity
XK-related protein 5. [Uniprot/SWISSPROT;Acc:Q6UX68]	1.17859	cellular component		integral to membrane
				membrane
Zinc finger and SCAN domain-containing protein 4 (Zinc finger protein 494). [Uniprot/SWISSPROT;Acc:Q8NAM6]	1.86204	biological process		regulation of transcription, DNA-dependent
				transcription
		cellular component		intracellular
				nucleus
		molecular function		metal ion binding
				nucleic acid binding
				transcription factor activity
				zinc ion binding
Zinc finger protein 202 (Zinc finger protein with KRAB and SCAN domains 10). [Uniprot/SWISSPROT;Acc:O95125]	1.89168	biological process		lipid metabolic process
				negative regulation of transcription from RNA polymerase II promoter
				regulation of transcription, DNA-dependent
				transcription
		cellular component		intracellular
				nucleus
		molecular function		DNA binding
				metal ion binding
				nucleic acid binding
				specific RNA polymerase II transcription factor activity
				transcription factor activity
				zinc ion binding
Zinc finger protein 219. [Uniprot/SWISSPROT;Acc:Q9P2Y4]	1.13007	biological process	up	anion transport
				G-protein coupled receptor protein signaling pathway
				regulation of transcription, DNA-dependent
		cellular component		integral to membrane
				intracellular
				membrane
				nucleus
		molecular function		histamine receptor activity
				inorganic anion exchanger activity
				metal ion binding
				nucleic acid binding
				transcription factor activity
				zinc ion binding

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.