MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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description	Ratio	Gene	Regulation	Class	Gene Ontology	Accession	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 2551 to 2600 of 2667 in total

description	Ratio	Regulation	Class	Gene Ontology
Voltage-dependent calcium channel gamma-7 subunit (Neuronal voltage- gated calcium channel gamma-7 subunit). [Uniprot/SWISSPROT;Acc:P62955]	3.41415	up	cellular component	voltage-gated calcium channel complex
			molecular function	calcium ion binding
				voltage-gated calcium channel activity
				voltage-gated ion channel activity
WAS protein homology region 2 domain containing 1 [RefSeq_peptide;Acc:NP_001073904]	1.54676	down	biological process	cell adhesion
			cellular component	actin cytoskeleton
				extracellular region
			molecular function	actin binding
				hormone activity
				structural molecule activity
Wee1-like protein kinase (EC 2.7.10.2) (Wee1A kinase) (WEE1hu). [Uniprot/SWISSPROT;Acc:P30291]	1.48363		biological process	cell cycle
				cell division
				mitosis
				protein amino acid phosphorylation
				regulation of progression through cell cycle
			cellular component	nucleus
			molecular function	ATP binding
				magnesium ion binding
				nucleotide binding
				protein binding
				protein kinase activity
				protein serine/threonine kinase activity
				protein-tyrosine kinase activity
				transferase activity
X box-binding protein 1 (XBP-1) (Tax-responsive element-binding protein 5). [Uniprot/SWISSPROT;Acc:P17861]	4.4149		biological process	immune response
				regulation of transcription
				regulation of transcription, DNA-dependent
				transcription
			cellular component	nucleus
			molecular function	DNA binding
				protein dimerization activity
				sequence-specific DNA binding
				transcription factor activity
XK-related protein 5. [Uniprot/SWISSPROT;Acc:Q6UX68]	1.17859		cellular component	integral to membrane
				membrane
Zinc finger and SCAN domain-containing protein 4 (Zinc finger protein 494). [Uniprot/SWISSPROT;Acc:Q8NAM6]	1.86204		biological process	regulation of transcription, DNA-dependent
				transcription
			cellular component	intracellular
				nucleus
			molecular function	metal ion binding
				nucleic acid binding
				transcription factor activity
				zinc ion binding
Zinc finger protein 202 (Zinc finger protein with KRAB and SCAN domains 10). [Uniprot/SWISSPROT;Acc:O95125]	1.89168		biological process	lipid metabolic process
				negative regulation of transcription from RNA polymerase II promoter
				regulation of transcription, DNA-dependent
				transcription
			cellular component	intracellular
				nucleus
			molecular function	DNA binding

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.