MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

description	Ratio	Regulation	Class	Gene Ontology	Gene	Accession	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 2451 to 2500 of 2667 in total

description	Ratio	Regulation	Class	Gene Ontology
Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC [Uniprot/SWISSPROT;Acc:Q9HBA0]	1.60668	up	molecular function	calcium channel activity
				calcium ion binding
				calmodulin binding
				identical protein binding
				ion channel activity
transient receptor potential cation channel, subfamily C, member 2 (TRPC2) on chromosome 11 [RefSeq_dna;Acc:NR_002720]	1.16158		biological process	calcium ion transport
				ion transport
			cellular component	membrane
			molecular function	calcium channel activity
				ion channel activity
transient receptor potential cation channel, subfamily M, member 1 [RefSeq_peptide;Acc:NP_002411]	2.8521		biological process	ion transport
			cellular component	integral to plasma membrane
				membrane
				membrane fraction
			molecular function	calcium channel activity
				ion channel activity
Transmembrane emp24 domain-containing protein 1 precursor (Interleukin-1 receptor-like 1 ligand) (Putative T1/ST2 receptor- binding protein). [Uniprot/SWISSPROT;Acc:Q13445]	1.14915		biological process	cell-cell signaling
				signal transduction
				transport
			cellular component	integral to membrane
				membrane
			molecular function	receptor binding
Transmembrane protein 116. [Uniprot/SWISSPROT;Acc:Q8NCL8]	1.82063	down	cellular component	integral to membrane
				membrane
Transmembrane protein 181. [Uniprot/SWISSPROT;Acc:Q9P2C4]	3.14866	up		integral to membrane
				membrane
Tripartite motif-containing protein 58 (Protein BIA2). [Uniprot/SWISSPROT;Acc:Q8NG06]	1.31489	down		intracellular
			molecular function	metal ion binding
				protein binding
				zinc ion binding
Tubulin-specific chaperone E (Tubulin-folding cofactor E). [Uniprot/SWISSPROT;Acc:Q15813]	5.84607		biological process	axonogenesis
				beta-tubulin folding
				microtubule cytoskeleton organization and biogenesis
				protein folding
				protein modification process
			cellular component	cytoplasm
				cytoskeleton
				microtubule
			molecular function	chaperone binding
				protein binding
Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14). [Uniprot/SWISSPROT;Acc:Q9H3S7]	1.62709	up	biological process	dephosphorylation
				protein amino acid dephosphorylation
			cellular component	cytoplasmic vesicle
			molecular function	hydrolase activity
				phosphoric monoester hydrolase activity
				protein tyrosine phosphatase activity
U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2) (Renal carcinoma antigen NY-REN-20). [Uniprot/SWISSPROT;Acc:Q15696]	1.07618		biological process	G-protein coupled receptor protein signaling pathway
				RNA splicing
			cellular component	integral to membrane
				nucleus

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.