MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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Class	Ratio	Regulation	description	Gene	Gene Ontology	Minimum Ratio	Accession	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 193 to 242 of 2667 in total

Class  : biological process

Ratio	Regulation	description	Gene Ontology
1.25729	up	Dehydrogenase/reductase SDR family member 1 (EC 1.1.-.-). [Uniprot/SWISSPROT;Acc:Q96LJ7]	enterobactin biosynthetic process
			metabolic process
1.25808		Chromodomain-helicase-DNA-binding protein 7 (EC 3.6.1.-) (ATP- dependent helicase CHD7) (CHD-7). [Uniprot/SWISSPROT;Acc:Q9P2D1]	adult heart development
			adult walking behavior
			blood vessel development
			camera-type eye development
			chromatin assembly or disassembly
			chromatin modification
			circulation
			embryonic hindlimb morphogenesis
			female genitalia development
			heart morphogenesis
			in utero embryonic development
			inner ear morphogenesis
			locomotory behavior
			nose development
			palate development
			positive regulation of body size
			regulation of transcription, DNA-dependent
			sensory perception of sound
			transcription
1.2734		Neurexin-2-alpha precursor (Neurexin II-alpha). [Uniprot/SWISSPROT;Acc:Q9P2S2]	cell adhesion
			neurotransmitter secretion
			synaptic transmission
			synaptogenesis
1.27461	down	Homeobox protein Hox-D3 (Hox-4A). [Uniprot/SWISSPROT;Acc:P31249]	anatomical structure morphogenesis
			G-protein coupled receptor protein signaling pathway
			multicellular organismal development
			regulation of transcription, DNA-dependent
			thyroid gland development
1.27696		Speedy protein A (Speedy-1) (Spy1) (Rapid inducer of G2/M progression in oocytes A) (RINGO A) (hSpy/Ringo A). [Uniprot/SWISSPROT;Acc:Q5MJ70]	cell cycle
			G1/S transition of mitotic cell cycle
			multicellular organismal development
			positive regulation of cell proliferation
			positive regulation of cyclin-dependent protein kinase activity
			protein amino acid dephosphorylation
			regulation of progression through cell cycle
			response to DNA damage stimulus
1.27802		Melanoma-associated antigen B2 (MAGE-B2 antigen) (DSS-AHC critical interval MAGE superfamily 6) (DAM6) (MAGE XP-2). [Uniprot/SWISSPROT;Acc:O15479]	homoiothermy
			response to freezing
1.28319	up	Autophagy-related protein 10 (APG10-like). [Uniprot/SWISSPROT;Acc:Q9H0Y0]	autophagy
			positive regulation of protein modification
			protein amino acid lipidation
			protein transport
			ubiquitin cycle
1.28356	down	T-box transcription factor TBX2 (T-box protein 2). [Uniprot/SWISSPROT;Acc:Q13207]	cardiac muscle development
			cell aging
			heart morphogenesis
			homoiothermy
			mammary gland development

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.