MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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description	Ratio	Gene	Regulation	Gene Ontology	Class	Accession	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 193 to 242 of 2667 in total

description	Ratio	Regulation	Gene Ontology	Class
ATP-binding cassette sub-family A member 3 (ATP-binding cassette transporter 3) (ATP-binding cassette 3) (ABC-C transporter). [Uniprot/SWISSPROT;Acc:Q99758]	1.22502	up	transport	biological process
			transporter activity	molecular function
ATP-binding domain 1 family member B. [Uniprot/SWISSPROT;Acc:Q9H9Y4]	3.06659	down	ATP binding
			nucleotide binding
ATPase family AAA domain-containing protein 2B. [Uniprot/SWISSPROT;Acc:Q9ULI0]	1.39878	up	ATP binding
			nucleoside-triphosphatase activity
			nucleotide binding
Autophagy-related protein 10 (APG10-like). [Uniprot/SWISSPROT;Acc:Q9H0Y0]	1.28319		autophagy	biological process
			cytoplasm	cellular component
			intracellular
			positive regulation of protein modification	biological process
			protein amino acid lipidation
			protein binding	molecular function
			protein transport	biological process
			ubiquitin cycle
Bardet-Biedl syndrome 5 protein. [Uniprot/SWISSPROT;Acc:Q8N3I7]	1.34491		cellular_component	cellular component
			cilium
			intracellular
			molecular_function	molecular function
			response to stimulus	biological process
			visual perception
Bcl-2-interacting killer (Apoptosis inducer NBK) (BP4) (BIP1). [Uniprot/SWISSPROT;Acc:Q13323]	1.21871	down	apoptotic program
			induction of apoptosis
			integral to membrane	cellular component
			membrane
			mitochondrial envelope
			protein binding	molecular function
			regulation of apoptosis	biological process
BET1 homolog (Golgi vesicular membrane-trafficking protein p18) (hBET1). [Uniprot/SWISSPROT;Acc:O15155]	2.48474	up	endoplasmic reticulum	cellular component
			ER to Golgi vesicle-mediated transport	biological process
			Golgi apparatus	cellular component
			Golgi membrane
			integral to membrane
			membrane
			protein binding	molecular function
			protein transport	biological process
Beta-defensin 2 precursor (BD-2) (hBD-2) (Defensin, beta 2) (Skin- antimicrobial peptide 1) (SAP1). [Uniprot/SWISSPROT;Acc:O15263]	1.51342	down	chemotaxis
			defense response
			defense response to bacterium
			extracellular region	cellular component
			G-protein coupled receptor protein signaling pathway	biological process
			immune response
Beta-mannosidase precursor (EC 3.2.1.25) (Lysosomal beta A mannosidase) (Mannanase) (Mannase). [Uniprot/SWISSPROT;Acc:O00462]	1.33329	up	beta-mannosidase activity	molecular function
			carbohydrate metabolic process	biological process
			cation binding	molecular function
			glycoprotein catabolic process	biological process
			hydrolase activity, hydrolyzing O-glycosyl compounds	molecular function
			lysosome	cellular component
			metabolic process	biological process
			protein modification process

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.