MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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Ratio	Regulation	description	Class	Gene Ontology	Gene	Accession	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 1651 to 1700 of 2667 in total

Ratio	Regulation	description	Class	Gene Ontology
1.89168	down	Zinc finger protein 202 (Zinc finger protein with KRAB and SCAN domains 10). [Uniprot/SWISSPROT;Acc:O95125]	molecular function	metal ion binding
				nucleic acid binding
				specific RNA polymerase II transcription factor activity
				transcription factor activity
				zinc ion binding
1.89308	up	Ras-related protein Rab-36. [Uniprot/SWISSPROT;Acc:O95755]	biological process	intracellular protein transport
				nucleocytoplasmic transport
				protein transport
				signal transduction
				small GTPase mediated signal transduction
			cellular component	Golgi apparatus
				intracellular
				membrane
			molecular function	GTP binding
				GTPase activity
				nucleotide binding
				protein binding
1.93863		Olfactory receptor 2B2 (Olfactory receptor 6-1) (OR6-1) (Hs6M1-10). [Uniprot/SWISSPROT;Acc:Q9GZK3]	biological process	G-protein coupled receptor protein signaling pathway
				response to stimulus
				sensory perception of smell
				signal transduction
			cellular component	integral to membrane
				membrane
			molecular function	olfactory receptor activity
				receptor activity
				rhodopsin-like receptor activity
1.93995		Zinc finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2). [Uniprot/SWISSPROT;Acc:Q92785]	biological process	apoptosis
				induction of apoptosis by extracellular signals
				regulation of transcription, DNA-dependent
				transcription
			cellular component	cytoplasm
				intracellular
				nucleus
			molecular function	metal ion binding
				nucleic acid binding
				protein binding
				zinc ion binding
1.95876		Ras-related protein Rab-17. [Uniprot/SWISSPROT;Acc:Q9H0T7]	biological process	intracellular protein transport
				nucleocytoplasmic transport
				protein transport
				signal transduction
				small GTPase mediated signal transduction
			cellular component	intracellular
			molecular function	GTP binding
				GTPase activity
				nucleotide binding
				protein binding
1.96673		Signal peptidase complex catalytic subunit SEC11C (EC 3.4.-.-) (SEC11 homolog C) (SEC11-like protein 3) (Microsomal signal peptidase 21 kDa subunit) (SPase 21 kDa subunit) (SPC21). [Uniprot/SWISSPROT;Acc:Q9BY50]	biological process	proteolysis
				signal peptide processing
			cellular component	endoplasmic reticulum

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.