MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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description	Ratio	Regulation	Class	Gene Ontology	Gene	Accession	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 1551 to 1600 of 2667 in total

description	Ratio	Regulation	Class	Gene Ontology
Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1). [Uniprot/SWISSPROT;Acc:Q9H4M7]	1.17693	up	molecular function	phosphatidylinositol binding
Pleckstrin homology-like domain family B member 2 (Protein LL5-beta). [Uniprot/SWISSPROT;Acc:Q86SQ0]	1.5415	down	biological process	chloride transport
				intracellular signaling cascade
				signal transduction
			cellular component	cytoplasm
				membrane
			molecular function	phospholipase C activity
				voltage-gated chloride channel activity
Podocalyxin-like protein 2 precursor (Endoglycan). [Uniprot/SWISSPROT;Acc:Q9NZ53]	1.15279	up	biological process	cell adhesion
			cellular component	integral to plasma membrane
				membrane
				viral capsid
			molecular function	glycosaminoglycan binding
				protein binding
				structural molecule activity
Poliovirus receptor-related protein 3 precursor (Nectin-3) (CD113 antigen) (CDw113). [Uniprot/SWISSPROT;Acc:Q9NQS3]	1.4628		biological process	cell adhesion
				homophilic cell adhesion
			cellular component	apical junction complex
				cell-cell adherens junction
				integral to membrane
				plasma membrane
			molecular function	protein binding
				protein homodimerization activity
				receptor activity
Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (HPCN3) (HGK5) (HuKIII) (HLK3). [Uniprot/SWISSPROT;Acc:P22001]	4.67988		biological process	dicarboxylic acid transport
				ion transport
				potassium ion transport
			cellular component	integral to membrane
				membrane
				membrane fraction
				voltage-gated potassium channel complex
			molecular function	delayed rectifier potassium channel activity
				ion channel activity
				outward rectifier potassium channel activity
				potassium ion binding
				protein binding
				sodium:dicarboxylate symporter activity
				voltage-gated ion channel activity
				voltage-gated potassium channel activity
Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4). [Uniprot/SWISSPROT;Acc:P56696]	1.17879		biological process	inner ear morphogenesis
				ion transport
				potassium ion transport
				sensory perception of sound
			cellular component	membrane
				membrane fraction
				voltage-gated potassium channel complex
			molecular function	ion channel activity
				potassium ion binding
				voltage-gated ion channel activity
				voltage-gated potassium channel activity

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.