MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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description	Ratio	Gene Ontology	Regulation	Class	Gene	Accession	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 151 to 200 of 1501 in total

Regulation  : up

description	Ratio	Gene Ontology	Class
CD40 ligand (CD40-L) (Tumor necrosis factor ligand superfamily member 5) (TNF-related activation protein) (TRAP) (T cell antigen Gp39) (CD154 antigen) [Contains: CD40 ligand, membrane form; CD40 ligand, soluble form]. [Uniprot/SWISSPROT;Acc:P29965]	1.98149	integral to plasma membrane	cellular component
		isotype switching	biological process
		leukocyte adhesion
		membrane	cellular component
		platelet activation	biological process
		regulation of immunoglobulin secretion
		soluble fraction	cellular component
		tumor necrosis factor receptor binding	molecular function
Centromere protein L (CENP-L) (Interphase centromere complex protein 33). [Uniprot/SWISSPROT;Acc:Q8N0S6]	1.78708	chromosome	cellular component
		chromosome, pericentric region
		nucleus
Centromere protein S (CENP-S) (Apoptosis-inducing TAF9-like domain- containing protein 1). [Uniprot/SWISSPROT;Acc:Q8N2Z9]	2.7017	chromosome
		chromosome organization and biogenesis (sensu Eukaryota)	biological process
		chromosome, pericentric region	cellular component
		DNA binding	molecular function
		extracellular region	cellular component
		G-protein signaling, adenylate cyclase inhibiting pathway	biological process
		G-protein-coupled receptor binding	molecular function
		hormone activity
		neuropeptide hormone activity
		nucleosome	cellular component
		nucleosome assembly	biological process
		nucleus	cellular component
		soluble fraction
		synaptic transmission	biological process
Chloride anion exchanger (Protein DRA) (Down-regulated in adenoma) (Solute carrier family 26 member 3). [Uniprot/SWISSPROT;Acc:P40879]	1.31661	anion exchanger activity	molecular function
		anion transport	biological process
		antiporter activity	molecular function
		apical plasma membrane	cellular component
		brush border membrane
		chloride ion binding	molecular function
		cytochrome complex assembly	biological process
		excretion
		heme transport
		heme transporter activity	molecular function
		integral to membrane	cellular component
		membrane
		membrane fraction
		sulfate porter activity	molecular function
		sulfate transport	biological process
		transcription cofactor activity	molecular function
		transcription factor activity
		transport	biological process
		transporter activity	molecular function
Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta). [Uniprot/SWISSPROT;Acc:Q14839]	1.78439	ATP binding
		ATP-dependent DNA helicase activity
		ATP-dependent helicase activity
		chromatin	cellular component
		chromatin assembly or disassembly	biological process
		chromatin binding	molecular function

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.