MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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description	Ratio	Regulation	Class	Gene Ontology	Gene	Accession	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 1390 to 1439 of 2667 in total

description	Ratio	Regulation	Class	Gene Ontology
Nuclear receptor-interacting protein 3 (Sarcoma antigen NY-SAR-105). [Uniprot/SWISSPROT;Acc:Q9NQ35]	3.32356	up	molecular function	aspartic-type endopeptidase activity
				sugar binding
Nuclear RNA export factor 2 (TAP-like protein 2) (TAPL-2). [Uniprot/SWISSPROT;Acc:Q9GZY0]	1.19207		biological process	mRNA export from nucleus
				multicellular organismal development
				transport
			cellular component	cytoplasm
				intracellular
				nuclear RNA export factor complex
				nucleus
			molecular function	nucleotide binding
				protein binding
				RNA binding
nucleolar and spindle associated protein 1 isoform 2 [RefSeq_peptide;Acc:NP_060924]	1.2984	down	biological process	cytokinesis after mitosis
				establishment of mitotic spindle localization
				mitotic chromosome condensation
				positive regulation of mitosis
			cellular component	nucleolus
				spindle microtubule
			molecular function	microtubule binding
Nucleolar preribosomal-associated protein 1 (Fragment). [Uniprot/SWISSPROT;Acc:O60287]	1.36755		biological process	biological_process
			cellular component	nucleolus
				nucleus
			molecular function	molecular_function
Nucleoplasmin-2. [Uniprot/SWISSPROT;Acc:Q86SE8]	5.83544		biological process	chromatin remodeling
				embryonic development
				oocyte differentiation
				positive regulation of meiosis
				regulation of exit from mitosis
				single fertilization
			cellular component	cytoplasmic chromatin
				nuclear chromatin
				nucleus
			molecular function	histone binding
				nucleic acid binding
NULL	1.18711	up		protein binding
	1.37553		biological process	protein folding
			molecular function	peptidyl-prolyl cis-trans isomerase activity
	1.40093			protein binding
	1.45314			DNA binding
	2.65068		biological process	complement activation
				proteolysis
			cellular component	extracellular region
			molecular function	calcium ion binding
				serine-type endopeptidase activity
olfactomedin-like 2A [RefSeq_peptide;Acc:NP_872293]	3.66058	down	cellular component	extracellular matrix
				membrane
			molecular function	extracellular matrix binding
				latrotoxin receptor activity
				protein homodimerization activity
Olfactory receptor 1J2 (Olfactory receptor OR9-19) (OST044) (HSA5) (HTPCRX15). [Uniprot/SWISSPROT;Acc:Q8NGS2]	2.86538	up	biological process	G-protein coupled receptor protein signaling pathway

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.