MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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description	Ratio	Regulation	Class	Gene Ontology	Gene	Accession	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 1340 to 1389 of 2667 in total

description	Ratio	Regulation	Class	Gene Ontology
Ninein-like protein. [Uniprot/SWISSPROT;Acc:Q9Y2I6]	3.15011	down	cellular component	microtubule
			molecular function	calcium ion binding
Nuclear factor of activated T-cells, cytoplasmic 3 (NF-ATc3) (NFATc3) (T cell transcription factor NFAT4) (NF-AT4) (NFATx). [Uniprot/SWISSPROT;Acc:Q12968]	5.32612		biological process	cellular respiration
				heart development
				inflammatory response
				regulation of transcription
				regulation of transcription from RNA polymerase II promoter
				regulation of transcription, DNA-dependent
			cellular component	cytoplasm
				nucleus
			molecular function	protein binding
				transcription coactivator activity
				transcription factor activity
Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa nucleoporin). [Uniprot/SWISSPROT;Acc:P49790]	1.48389		biological process	ATP synthesis coupled proton transport
				intracellular protein transport across a membrane
				mRNA transport
				protein transport
			cellular component	intracellular
				nuclear pore
				nucleus
				proton-transporting two-sector ATPase complex
			molecular function	ATP binding
				DNA binding
				hydrogen ion transporting ATP synthase activity, rotational mechanism
				hydrogen ion transporting ATPase activity, rotational mechanism
				metal ion binding
				protein binding
				transporter activity
				zinc ion binding
Nuclear receptor ROR-alpha (Retinoid-related orphan receptor-alpha) (Nuclear receptor RZR-alpha). [Uniprot/SWISSPROT;Acc:P35398]	1.98137		biological process	regulation of transcription, DNA-dependent
				signal transduction
				transcription
			cellular component	nucleus
			molecular function	DNA binding
				ligand-dependent nuclear receptor activity
				metal ion binding
				protein binding
				sequence-specific DNA binding
				steroid hormone receptor activity
				thyroid hormone receptor activity
				transcription factor activity
				zinc ion binding
Nuclear receptor-binding factor 2 (NRBF-2) (Comodulator of PPAR and RXR). [Uniprot/SWISSPROT;Acc:Q96F24]	1.10889	up	biological process	regulation of transcription, DNA-dependent
				transcription
			cellular component	cytoplasm
				nucleus
			molecular function	protein dimerization activity
				sequence-specific DNA binding
				transcription factor activity
Nuclear receptor-interacting protein 3 (Sarcoma antigen NY-SAR-105). [Uniprot/SWISSPROT;Acc:Q9NQ35]	3.32356		biological process	proteolysis

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.