MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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Ratio	Accession	description	Regulation	Class	Gene Ontology	Gene	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 951 to 1000 of 2667 in total

Ratio	description	Regulation	Class	Gene Ontology
1.37411	Lariat debranching enzyme (EC 3.1.-.-). [Uniprot/SWISSPROT;Acc:Q9UK59]	up	biological process	mRNA processing
				nuclear mRNA splicing, via spliceosome
				RNA splicing, via transesterification reactions
			cellular component	nucleus
			molecular function	hydrolase activity
				hydrolase activity, acting on ester bonds
				metal ion binding
				RNA lariat debranching enzyme activity
1.37553	NULL		biological process	protein folding
			molecular function	peptidyl-prolyl cis-trans isomerase activity
1.37801	Glycerophosphodiester phosphodiesterase domain-containing protein 2 (EC 3.1.-.-) (Glycerophosphodiester phosphodiesterase 3) (Osteoblast differentiation promoting factor). [Uniprot/SWISSPROT;Acc:Q9HCC8]		biological process	glycerol metabolic process
				metabolic process
			cellular component	cytoplasm
				cytoskeleton
				integral to membrane
				membrane
			molecular function	glycerophosphodiester phosphodiesterase activity
				hydrolase activity
1.39878	ATPase family AAA domain-containing protein 2B. [Uniprot/SWISSPROT;Acc:Q9ULI0]			ATP binding
				nucleoside-triphosphatase activity
				nucleotide binding
1.40093	NULL			protein binding
1.40451	COX16-like protein C14orf112, mitochondrial precursor. [Uniprot/SWISSPROT;Acc:Q9P0S2]	down	cellular component	integral to membrane
				membrane
				mitochondrion
1.40552	Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) (Amino acid transporter ATB0+) (Solute carrier family 6 member 14). [Uniprot/SWISSPROT;Acc:Q9UN76]		biological process	amino acid metabolic process
				amino acid transport
				dicarboxylic acid transport
				neurotransmitter transport
			cellular component	integral to plasma membrane
				membrane
			molecular function	amino acid transporter activity
				neurotransmitter:sodium symporter activity
				sodium:dicarboxylate symporter activity
				symporter activity
1.40602	GTP-binding protein SAR1a (COPII-associated small GTPase). [Uniprot/SWISSPROT;Acc:Q9NR31]	up	biological process	ER to Golgi vesicle-mediated transport
				intracellular protein transport
				small GTPase mediated signal transduction
			cellular component	cytoplasm
				endoplasmic reticulum
				Golgi apparatus
				intracellular
			molecular function	GTP binding
				GTPase activity
				nucleotide binding
1.40749	collagen, type XXVII, alpha 1 [RefSeq_peptide;Acc:NP_116277]		biological process	cell adhesion
				G-protein coupled receptor protein signaling pathway
				phosphate transport
			cellular component	collagen
				cytoplasm

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.