Scientific
MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis
These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.
Affected Genes

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Ratio Regulation description Class Gene Ontology Gene Accession Minimum Ratio Maximum Ratio
Results: HTML CSV LaTeX
Showing element 551 to 600 of 2667 in total
Ratio	Regulation	description	Class	Gene Ontology	
1.25147	up	T-lymphocyte activation antigen CD86 precursor (Activation B7-2 antigen) (CTLA-4 counter-receptor B7.2) (B70) (FUN-1) (BU63). [Source:Uniprot/SWISSPROT;Acc:P42081]	biological process	T cell activation	
1.25147	up	T-lymphocyte activation antigen CD86 precursor (Activation B7-2 antigen) (CTLA-4 counter-receptor B7.2) (B70) (FUN-1) (BU63). [Source:Uniprot/SWISSPROT;Acc:P42081]	biological process	T cell proliferation	
1.25147	up	T-lymphocyte activation antigen CD86 precursor (Activation B7-2 antigen) (CTLA-4 counter-receptor B7.2) (B70) (FUN-1) (BU63). [Source:Uniprot/SWISSPROT;Acc:P42081]	cellular component	external side of plasma membrane	
1.25147	up	T-lymphocyte activation antigen CD86 precursor (Activation B7-2 antigen) (CTLA-4 counter-receptor B7.2) (B70) (FUN-1) (BU63). [Source:Uniprot/SWISSPROT;Acc:P42081]	cellular component	integral to membrane	
1.25147	up	T-lymphocyte activation antigen CD86 precursor (Activation B7-2 antigen) (CTLA-4 counter-receptor B7.2) (B70) (FUN-1) (BU63). [Source:Uniprot/SWISSPROT;Acc:P42081]	cellular component	plasma membrane	
1.25147	up	T-lymphocyte activation antigen CD86 precursor (Activation B7-2 antigen) (CTLA-4 counter-receptor B7.2) (B70) (FUN-1) (BU63). [Source:Uniprot/SWISSPROT;Acc:P42081]	molecular function	coreceptor activity	
1.25147	up	T-lymphocyte activation antigen CD86 precursor (Activation B7-2 antigen) (CTLA-4 counter-receptor B7.2) (B70) (FUN-1) (BU63). [Source:Uniprot/SWISSPROT;Acc:P42081]	molecular function	protein binding	
1.25147	up	T-lymphocyte activation antigen CD86 precursor (Activation B7-2 antigen) (CTLA-4 counter-receptor B7.2) (B70) (FUN-1) (BU63). [Source:Uniprot/SWISSPROT;Acc:P42081]	molecular function	transcriptional activator activity	
1.25205	down	Protein CWC15 homolog. [Source:Uniprot/SWISSPROT;Acc:Q9P013]	biological process	nuclear mRNA splicing, via spliceosome	
1.25205	down	Protein CWC15 homolog. [Source:Uniprot/SWISSPROT;Acc:Q9P013]	biological process	RNA splicing	
1.25205	down	Protein CWC15 homolog. [Source:Uniprot/SWISSPROT;Acc:Q9P013]	biological process	SRP-dependent cotranslational protein targeting to membrane	
1.25205	down	Protein CWC15 homolog. [Source:Uniprot/SWISSPROT;Acc:Q9P013]	cellular component	membrane	
1.25205	down	Protein CWC15 homolog. [Source:Uniprot/SWISSPROT;Acc:Q9P013]	cellular component	nucleus	
1.25205	down	Protein CWC15 homolog. [Source:Uniprot/SWISSPROT;Acc:Q9P013]	cellular component	spliceosome	
1.25205	down	Protein CWC15 homolog. [Source:Uniprot/SWISSPROT;Acc:Q9P013]	molecular function	7S RNA binding	
1.25205	down	Protein CWC15 homolog. [Source:Uniprot/SWISSPROT;Acc:Q9P013]	molecular function	GTP binding	
1.25205	down	Protein CWC15 homolog. [Source:Uniprot/SWISSPROT;Acc:Q9P013]	molecular function	RNA binding	
1.25729	up	Dehydrogenase/reductase SDR family member 1 (EC 1.1.-.-). [Source:Uniprot/SWISSPROT;Acc:Q96LJ7]	biological process	enterobactin biosynthetic process	
1.25729	up	Dehydrogenase/reductase SDR family member 1 (EC 1.1.-.-). [Source:Uniprot/SWISSPROT;Acc:Q96LJ7]	biological process	metabolic process	
1.25729	up	Dehydrogenase/reductase SDR family member 1 (EC 1.1.-.-). [Source:Uniprot/SWISSPROT;Acc:Q96LJ7]	cellular component	endoplasmic reticulum	
1.25729	up	Dehydrogenase/reductase SDR family member 1 (EC 1.1.-.-). [Source:Uniprot/SWISSPROT;Acc:Q96LJ7]	cellular component	mitochondrial inner membrane	
1.25729	up	Dehydrogenase/reductase SDR family member 1 (EC 1.1.-.-). [Source:Uniprot/SWISSPROT;Acc:Q96LJ7]	molecular function	2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase activity	
1.25729	up	Dehydrogenase/reductase SDR family member 1 (EC 1.1.-.-). [Source:Uniprot/SWISSPROT;Acc:Q96LJ7]	molecular function	oxidoreductase activity	
1.25808	up	Chromodomain-helicase-DNA-binding protein 7 (EC 3.6.1.-) (ATP- dependent helicase CHD7) (CHD-7). [Source:Uniprot/SWISSPROT;Acc:Q9P2D1]	biological process	adult heart development	
1.25808	up	Chromodomain-helicase-DNA-binding protein 7 (EC 3.6.1.-) (ATP- dependent helicase CHD7) (CHD-7). [Source:Uniprot/SWISSPROT;Acc:Q9P2D1]	biological process	adult walking behavior	
1.25808	up	Chromodomain-helicase-DNA-binding protein 7 (EC 3.6.1.-) (ATP- dependent helicase CHD7) (CHD-7). [Source:Uniprot/SWISSPROT;Acc:Q9P2D1]	biological process	blood vessel development	
1.25808	up	Chromodomain-helicase-DNA-binding protein 7 (EC 3.6.1.-) (ATP- dependent helicase CHD7) (CHD-7). [Source:Uniprot/SWISSPROT;Acc:Q9P2D1]	biological process	camera-type eye development	
1.25808	up	Chromodomain-helicase-DNA-binding protein 7 (EC 3.6.1.-) (ATP- dependent helicase CHD7) (CHD-7). [Source:Uniprot/SWISSPROT;Acc:Q9P2D1]	biological process	chromatin assembly or disassembly	
1.25808	up	Chromodomain-helicase-DNA-binding protein 7 (EC 3.6.1.-) (ATP- dependent helicase CHD7) (CHD-7). [Source:Uniprot/SWISSPROT;Acc:Q9P2D1]	biological process	chromatin modification	
1.25808	up	Chromodomain-helicase-DNA-binding protein 7 (EC 3.6.1.-) (ATP- dependent helicase CHD7) (CHD-7). [Source:Uniprot/SWISSPROT;Acc:Q9P2D1]	biological process	circulation	
1.25808	up	Chromodomain-helicase-DNA-binding protein 7 (EC 3.6.1.-) (ATP- dependent helicase CHD7) (CHD-7). [Source:Uniprot/SWISSPROT;Acc:Q9P2D1]	biological process	embryonic hindlimb morphogenesis	
1.25808	up	Chromodomain-helicase-DNA-binding protein 7 (EC 3.6.1.-) (ATP- dependent helicase CHD7) (CHD-7). [Source:Uniprot/SWISSPROT;Acc:Q9P2D1]	biological process	female genitalia development	
1.25808	up	Chromodomain-helicase-DNA-binding protein 7 (EC 3.6.1.-) (ATP- dependent helicase CHD7) (CHD-7). [Source:Uniprot/SWISSPROT;Acc:Q9P2D1]	biological process	heart morphogenesis	
1.25808	up	Chromodomain-helicase-DNA-binding protein 7 (EC 3.6.1.-) (ATP- dependent helicase CHD7) (CHD-7). [Source:Uniprot/SWISSPROT;Acc:Q9P2D1]	biological process	in utero embryonic development	
1.25808	up	Chromodomain-helicase-DNA-binding protein 7 (EC 3.6.1.-) (ATP- dependent helicase CHD7) (CHD-7). [Source:Uniprot/SWISSPROT;Acc:Q9P2D1]	biological process	inner ear morphogenesis	
1.25808	up	Chromodomain-helicase-DNA-binding protein 7 (EC 3.6.1.-) (ATP- dependent helicase CHD7) (CHD-7). [Source:Uniprot/SWISSPROT;Acc:Q9P2D1]	biological process	locomotory behavior	
1.25808	up	Chromodomain-helicase-DNA-binding protein 7 (EC 3.6.1.-) (ATP- dependent helicase CHD7) (CHD-7). [Source:Uniprot/SWISSPROT;Acc:Q9P2D1]	biological process	nose development	
1.25808	up	Chromodomain-helicase-DNA-binding protein 7 (EC 3.6.1.-) (ATP- dependent helicase CHD7) (CHD-7). [Source:Uniprot/SWISSPROT;Acc:Q9P2D1]	biological process	palate development	
1.25808	up	Chromodomain-helicase-DNA-binding protein 7 (EC 3.6.1.-) (ATP- dependent helicase CHD7) (CHD-7). [Source:Uniprot/SWISSPROT;Acc:Q9P2D1]	biological process	positive regulation of body size	
1.25808	up	Chromodomain-helicase-DNA-binding protein 7 (EC 3.6.1.-) (ATP- dependent helicase CHD7) (CHD-7). [Source:Uniprot/SWISSPROT;Acc:Q9P2D1]	biological process	regulation of transcription, DNA-dependent	
1.25808	up	Chromodomain-helicase-DNA-binding protein 7 (EC 3.6.1.-) (ATP- dependent helicase CHD7) (CHD-7). [Source:Uniprot/SWISSPROT;Acc:Q9P2D1]	biological process	sensory perception of sound	
1.25808	up	Chromodomain-helicase-DNA-binding protein 7 (EC 3.6.1.-) (ATP- dependent helicase CHD7) (CHD-7). [Source:Uniprot/SWISSPROT;Acc:Q9P2D1]	biological process	transcription	
1.25808	up	Chromodomain-helicase-DNA-binding protein 7 (EC 3.6.1.-) (ATP- dependent helicase CHD7) (CHD-7). [Source:Uniprot/SWISSPROT;Acc:Q9P2D1]	cellular component	chromatin	
1.25808	up	Chromodomain-helicase-DNA-binding protein 7 (EC 3.6.1.-) (ATP- dependent helicase CHD7) (CHD-7). [Source:Uniprot/SWISSPROT;Acc:Q9P2D1]	cellular component	nucleus	
1.25808	up	Chromodomain-helicase-DNA-binding protein 7 (EC 3.6.1.-) (ATP- dependent helicase CHD7) (CHD-7). [Source:Uniprot/SWISSPROT;Acc:Q9P2D1]	molecular function	ATP binding	
1.25808	up	Chromodomain-helicase-DNA-binding protein 7 (EC 3.6.1.-) (ATP- dependent helicase CHD7) (CHD-7). [Source:Uniprot/SWISSPROT;Acc:Q9P2D1]	molecular function	chromatin binding	
1.25808	up	Chromodomain-helicase-DNA-binding protein 7 (EC 3.6.1.-) (ATP- dependent helicase CHD7) (CHD-7). [Source:Uniprot/SWISSPROT;Acc:Q9P2D1]	molecular function	DNA binding	
1.25808	up	Chromodomain-helicase-DNA-binding protein 7 (EC 3.6.1.-) (ATP- dependent helicase CHD7) (CHD-7). [Source:Uniprot/SWISSPROT;Acc:Q9P2D1]	molecular function	helicase activity	
1.25808	up	Chromodomain-helicase-DNA-binding protein 7 (EC 3.6.1.-) (ATP- dependent helicase CHD7) (CHD-7). [Source:Uniprot/SWISSPROT;Acc:Q9P2D1]	molecular function	hydrolase activity	
1.25808	up	Chromodomain-helicase-DNA-binding protein 7 (EC 3.6.1.-) (ATP- dependent helicase CHD7) (CHD-7). [Source:Uniprot/SWISSPROT;Acc:Q9P2D1]	molecular function	nucleic acid binding	

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells. 
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component. 
- The Gene Ontology terms as linked to the specific gene.
- http://analysis.yellowcouch.org/